A STUDY ON THE DISSOLUTION OF DIRECTLY COMPRESSED DIIODOQUIN TABLETS | ||
| Bulletin of Pharmaceutical Sciences Assiut University | ||
| Article 9, Volume 6, Issue 1, June 1983, Pages 123-134 PDF (418.25 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bfsa.1983.100950 | ||
| Authors | ||
| A. E. Aboutaleb; S. A. Tout | ||
| Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt | ||
| Abstract | ||
| The effect of certain directly compressible vehicles on the dissolution rate of directly compressed diiodoquin tablets was investigated. Different tablet formulations containing various vehicles were selected for this study. Tablets investigated were prepared using different proportions of either single or binary blends of vehicles and was found to possess different disintegration times. A significant correlation was obtained between the dissolution time (T50) and the disintegration time. The dissolution rate was dependent on the type of vehicle used and its actual concentration in the formula. Other factors such as the type and concentration of the lubricant (S), hardness values of the tablets prepared, solubility of the drug as well as interactions between the drug and vehicles used may also, play a part. | ||
|
Statistics Article View: 97 PDF Download: 144 |
||
