EFFECT OF BINARY BLEND OF VEHICLES ON THE PHYSICAL PROPERTIES OF DIRECTLY COMPRESSED DIIODOQUIN TABLETS | ||
| Bulletin of Pharmaceutical Sciences Assiut University | ||
| Article 10, Volume 6, Issue 1, June 1983, Pages 135-153 PDF (737.76 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bfsa.1983.100951 | ||
| Authors | ||
| A. E. Ahoutaleb; S. A. Tout | ||
| Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt | ||
| Abstract | ||
| Directly compressible vehicles such as Avicel, Emdex, Sugratab, Anhydrous Lactose U.S.P, STA-R 1500 starch and Fmcompress, were used either singly or in binary blends in the ratios of 1:1, 1:3 and 3:1 w/w for the preparation diiodoquin tablets. Avicel, Celutab and STA-Rx 1500 starch were found to be the most suitable single vehicles for the formulation of diiodoquin tablets. Tablets produced using STA-R and its blends with the other vehicles, disintegrated within the specified time. The best blends used for the manufacturing of directly compressed diiodoquin tablets were those containing avicel/STA-Rx 1500 starch 3:1 and 1:3. The least actual concentration of the vehicle needed for the preparation of good diiodoquin tablets was not less than 42.0% w/w. | ||
|
Statistics Article View: 90 PDF Download: 200 |
||
