Aboutaleb, A., Ahmed, S. (1983). EFFECT OF PH, TEMPERATURE AND CERTAIN ADDITIVES ON THE SOLUBILIZATION OF CARBAMAZEPINE BY SELECTED NON-IONIC SURFACTANT SOLUTIONS. test, 6(2), 321-334. doi: 10.21608/bfsa.1983.102092
A. E. Aboutaleb; S. M. Ahmed. "EFFECT OF PH, TEMPERATURE AND CERTAIN ADDITIVES ON THE SOLUBILIZATION OF CARBAMAZEPINE BY SELECTED NON-IONIC SURFACTANT SOLUTIONS". test, 6, 2, 1983, 321-334. doi: 10.21608/bfsa.1983.102092
Aboutaleb, A., Ahmed, S. (1983). 'EFFECT OF PH, TEMPERATURE AND CERTAIN ADDITIVES ON THE SOLUBILIZATION OF CARBAMAZEPINE BY SELECTED NON-IONIC SURFACTANT SOLUTIONS', test, 6(2), pp. 321-334. doi: 10.21608/bfsa.1983.102092
Aboutaleb, A., Ahmed, S. EFFECT OF PH, TEMPERATURE AND CERTAIN ADDITIVES ON THE SOLUBILIZATION OF CARBAMAZEPINE BY SELECTED NON-IONIC SURFACTANT SOLUTIONS. test, 1983; 6(2): 321-334. doi: 10.21608/bfsa.1983.102092

EFFECT OF PH, TEMPERATURE AND CERTAIN ADDITIVES ON THE SOLUBILIZATION OF CARBAMAZEPINE BY SELECTED NON-IONIC SURFACTANT SOLUTIONS

Bulletin of Pharmaceutical Sciences Assiut University
Article 6, Volume 6, Issue 2, December 1983, Pages 321-334    PDF (485.22 K)
Document Type: Original Article
DOI: 10.21608/bfsa.1983.102092
Authors
A. E. Aboutaleb; S. M. Ahmed
Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
Abstract
The effect of incorporation of various organic additives on the solvent power of the different micelles for Carbamazepine was investigated. The variation in the pH value as well as the temperature of these solution on the degree of solubilization of Carbamazepine was also studied.
It was found that propylene glycol increased the solvent power of the different micelles, while glycerol, and PEG 1000, 4000 and 6000 decrease their solubilizing capacity. Raising the temperature and lowering of pH value also increased the solvent power of the micelles.
Statistics
Article View: 93
PDF Download: 150