Ratio between Low Serum Maternal 25-Hydroxy vitamin D Concentration and the Risk of Preeclampsia | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 16, Volume 72, Issue 8, July 2018, Pages 5044-5049 PDF (523.11 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2018.10285 | ||
| Authors | ||
| Ahmed Abdelshafy Abdelhafiz* ; Samir Abdalla Ali; Tamer Faris; Ahmed Fathy Abd Elaziz | ||
| Department of Obstetrics and Gynecology, Faculty of Medicine-al-Azhar University | ||
| Abstract | ||
| Background: Vitamin D may play a role in the etiology of preeclampsia by regulating the transcription and function of genes associated with placental function, including placental invasion, normal implantation, and angiogenesis. Vitamin D also, modulates immune function and inflammatory response. Maternal vitamin D concentration may be influenced by several factors, including diet, supplementation, sun exposure, skin pigmentation, and genetics. Therefore, vitamin D deficiency is a potentially modifiable risk factor for preeclampsia. Objective: To find out if lower levels of vitamin D is more prevalent in preeclamptic women. Patients and Methods: This study carried out on 50 pregnant women recruited at pre labour room. They divided into preeclamptic group and non-preeclamptic group, 25 cases in each group. Current study was conducted as a case-control study to compare vitamin D level between preeclamptic and non-preeclamptic women at Al-Hussein University Hospital as current study recruited 50 primigravida. Women after 36 weeks of gestation without any other medical disorders. They were classified into preeclamptic case group and normotensive control group. Results: The current study found that vitamin D levels were lower in preeclamptic group than normotensive control group but these differences were not statistically significant. | ||
| Keywords | ||
| Pregnancy; preeclampsia; Hypertension; vitamin D deficiency; 25-Hydroxyvitamin D | ||
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