Aboutaleb, A., Attia, M., Habib, F. (1982). DISSOLUTION STUDY ON SULPHAPYRIDINE, AND SULPHISOXAZOLE FROM THEIR SOLID DISPERSIONS AND COPRECIPITATES. test, 5(1), 117-128. doi: 10.21608/bfsa.1982.103037
A. E. Aboutaleb; M. A. Attia; F. S. Habib. "DISSOLUTION STUDY ON SULPHAPYRIDINE, AND SULPHISOXAZOLE FROM THEIR SOLID DISPERSIONS AND COPRECIPITATES". test, 5, 1, 1982, 117-128. doi: 10.21608/bfsa.1982.103037
Aboutaleb, A., Attia, M., Habib, F. (1982). 'DISSOLUTION STUDY ON SULPHAPYRIDINE, AND SULPHISOXAZOLE FROM THEIR SOLID DISPERSIONS AND COPRECIPITATES', test, 5(1), pp. 117-128. doi: 10.21608/bfsa.1982.103037
Aboutaleb, A., Attia, M., Habib, F. DISSOLUTION STUDY ON SULPHAPYRIDINE, AND SULPHISOXAZOLE FROM THEIR SOLID DISPERSIONS AND COPRECIPITATES. test, 1982; 5(1): 117-128. doi: 10.21608/bfsa.1982.103037

DISSOLUTION STUDY ON SULPHAPYRIDINE, AND SULPHISOXAZOLE FROM THEIR SOLID DISPERSIONS AND COPRECIPITATES

Bulletin of Pharmaceutical Sciences Assiut University
Article 9, Volume 5, Issue 1, 1982, Pages 117-128    PDF (318.27 K)
Document Type: Original Article
DOI: 10.21608/bfsa.1982.103037
Authors
A. E. Aboutaleb; M. A. Attia; F. S. Habib
Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
Abstract
sulphisoxazole was investigated from their solid dispersions using PEG 4000, 6000 and coprecipitates using PVP 25,000. It was found that the rate of dissolution was much greater from the preparations containing solid dispersions as well as co-precipitates for the three sulphonamides investigated. The polymer to drug ratio and the molecular structure, as well as the nature of the polymer may also affect the rate of release of each sulphonamide from its different formulations.
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