The Efficacy of Diphenylcyclopropenone in Treatment of Molluscum Contagiosum | ||
| Zagazig University Medical Journal | ||
| Article 22, Volume 29, Issue 1.1, January 2023, Pages 151-158 PDF (411.11 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zumj.2020.34318.1890 | ||
| Authors | ||
| Samia Ali Ibrahim1; Marwa Mohamed Fathy2; Nesma Elsayed Abd Elmoniem* 3; Howyda Mohamed Ebrahim4 | ||
| 1Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Zagazig University, Zagazig, Egypt | ||
| 2Department of Dermatology, Venereology and Andrology,Faculty of Medicine, Zagazig University, Zagazig, Egypt, | ||
| 3Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Zagazig University, Zagazig,Egypt, | ||
| 4Zagazig University Hospital | ||
| Abstract | ||
| Abstract Background Diphenylcyclopropenone (DPCP) contact immunotherapy has been successfully utilized in various forms for treatments of recalcitrant and facial warts, molluscum contagiosum (MC) and alopecia areata. Objective The objective was to evaluate the safety and efficacy of DPCP in the treatment of MC. Patients and Methods Twenty-four patients with MC were assigned to two groups: twelve patients (group A) were treated with topical application of DPCP one session per week for a maximum of 12 sessions or until clinical cure. Also, twelve patients (group B) were subjected to topical application of normal neutral saline as a control group. Follow-up was done for 3 months. Results In group A, eight patients (66.7%) showed complete response while four patients (33.3%) showed partial response to the topical application of DPCP after seven to twelve sessions. However, in group B, eleven patients (91.7%) showed no response and (8.3%) showed partial response. A highly significant difference was found in the clinical response between both groups (p < /p> | ||
| Keywords | ||
| Molluscumcontagiosum; Diphenylcyclopropenone; immunotherapy | ||
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