Synthesis and Antibacterial Activity of Schiff Base Compounds Derived from Glyoxal, Vanillin with Their Complexes with Iron (ш) | ||
| Egyptian Journal of Chemistry | ||
| Article 37, Volume 63, Issue 10, October 2020, Pages 3985-3994 PDF (950.07 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2020.31555.2699 | ||
| Authors | ||
| zainab J J.sweah* 1; mariam Abdul-bary Auribie2 | ||
| 1Basrah/Qarmat ali | ||
| 2College of Agriculture. Basrah University, Iraq. | ||
| Abstract | ||
| In this study, a library of Schiff bases derived from aliphatic (Glyoxal) and aromatic (Vanillin) aldehydes with different substituted aniline compounds. In addition to their complexes with Iron (III) were synthesized. The synthesized compounds were characterized by chemical and physical techniques (IR, 1H-NMR, melting point, color, UV-Visible). The library of the Schiff bases and their complexes were tested against two types of human pathogen bacteria (Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative)). in a public way, The Fe+3 complexes were relatively more active against Escherichia coli than the corresponding Schiff bases. The antibacterial activities of the Schiff bases and their complexes against Staphylococcus aureus were variable. | ||
| Keywords | ||
| Schiff bases; glyoxal; vanillin; metal complexes; antibacterial | ||
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