YASSIN, M., ZIDAN, T., MELEK, S., RASHED, M. (2016). Immunological study for Helicobacter pylori bacteria in Egyptian patients.. test, 2(12), 758-763. doi: 10.21608/jbaar.2016.109752
MOHAMED H. YASSIN; TAGHREED A. ZIDAN; SAMUEL T. MELEK; MOHAMED E. RASHED. "Immunological study for Helicobacter pylori bacteria in Egyptian patients.". test, 2, 12, 2016, 758-763. doi: 10.21608/jbaar.2016.109752
YASSIN, M., ZIDAN, T., MELEK, S., RASHED, M. (2016). 'Immunological study for Helicobacter pylori bacteria in Egyptian patients.', test, 2(12), pp. 758-763. doi: 10.21608/jbaar.2016.109752
YASSIN, M., ZIDAN, T., MELEK, S., RASHED, M. Immunological study for Helicobacter pylori bacteria in Egyptian patients.. test, 2016; 2(12): 758-763. doi: 10.21608/jbaar.2016.109752

Immunological study for Helicobacter pylori bacteria in Egyptian patients.

Journal of Bioscience and Applied Research
Article 3, Volume 2, Issue 12, December 2016, Pages 758-763    PDF (417.37 K)
Document Type: Original Article
DOI: 10.21608/jbaar.2016.109752
Authors
MOHAMED H. YASSIN1; TAGHREED A. ZIDAN1; SAMUEL T. MELEK2; MOHAMED E. RASHED3, 1
1Botany Department, Faculty of Science Benha University, Benha, Egypt.
2Parasitology and Blood Research Department, National Organization for Drug Control and Research (NODCAR), Cairo, Egypt.
3Microbiology Department, National organization for Research and Control of Biologicals (NORCB),Cairo, Egypt.
Abstract
Helicobacter pylori (H. Pylori) are a helix shaped, microaerophilic, Gram-negative, flagellated bacteria. H. Pylori and mankind have an ancient relationship for at least 50,000 years. Commonly the first noninvasively testes used for H. pylori infection’s detection were immunological tests like blood antibody test and stool antigen test. We investigated the more efficient susceptibility immunological test for detection of H.pylori infection in adult Egyptian patients by comparing the results of H. Pylori IgA (HpIgA), IgG in serum blood (HpIgG) and H.pylori Ag in stool (HpSAg) for 30 adult patient against control group using ELISA technique. The results showed that each test could be used successfully for diagnosis of H. pylori. Finally HpSAg showed reliable results with high sensitivity (> 95%) followed by HpIgG (87.5%), while HpIgA showed the lowest sensitivity (37.5%). Our findings confirms the use of the mentioned immunological tests for detecting them H. Pylori infection and suggest the use H. Pylori Ag in stool as the most economic, sensitive and reliable method alone or followed by IgG antibody test as confirmatory test to be the first choices for early diagnosis of H. Pylori especially in developing countries.
Keywords
Helicobacter pylori; immunological test; IgA; IgG; patients
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