ElKhateeb, A., Hussein, S., Salem, M., El Negoumy, S. (2019). LC-ESI-MS Analysis, Antitumor and Antiviral Activities of Bosica senegalensis Aqueous Methanolic Extract. test, 62(1), 77-83. doi: 10.21608/ejchem.2018.4828.1428
Ahmed ElKhateeb; Sameh Hussein; Maha Salem; Sabry El Negoumy. "LC-ESI-MS Analysis, Antitumor and Antiviral Activities of Bosica senegalensis Aqueous Methanolic Extract". test, 62, 1, 2019, 77-83. doi: 10.21608/ejchem.2018.4828.1428
ElKhateeb, A., Hussein, S., Salem, M., El Negoumy, S. (2019). 'LC-ESI-MS Analysis, Antitumor and Antiviral Activities of Bosica senegalensis Aqueous Methanolic Extract', test, 62(1), pp. 77-83. doi: 10.21608/ejchem.2018.4828.1428
ElKhateeb, A., Hussein, S., Salem, M., El Negoumy, S. LC-ESI-MS Analysis, Antitumor and Antiviral Activities of Bosica senegalensis Aqueous Methanolic Extract. test, 2019; 62(1): 77-83. doi: 10.21608/ejchem.2018.4828.1428

LC-ESI-MS Analysis, Antitumor and Antiviral Activities of Bosica senegalensis Aqueous Methanolic Extract

Egyptian Journal of Chemistry
Article 7, Volume 62, Issue 1, January 2019, Pages 77-83    PDF (547.98 K)
Document Type: Original Article
DOI: 10.21608/ejchem.2018.4828.1428
Authors
Ahmed ElKhateeb* ; Sameh Hussein; Maha Salem; Sabry El Negoumy
National Research Center
Abstract
Twenty one compounds (twelve flavonoids, four benzoylglucarate isomers, two phenolic acids, two glucosinolates, and one saccharide) were identified from the B. senegalensis aqueous methanolic extract using LC-ESI-MS technique. Among the identified compounds, quercetin-O-sinapoylglucoside-O-glucoside (13) and quercetin-di-O-benzoyl glucoside (16) are newly identified natural products.
B. senegalensis aqueous methanolic extract showed strong inhibitory effect against H5N1 viruses and moderate antitumor activity against three carcinoma cell lines.
Keywords
Boscia senegalensis; Capparaceae; LC-ESI-MS; antitumor; Antiviral
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