Green Synthesis of Zinc Oxide Nanoparticles Using Portulaca oleracea (Regla Seeds) Extract and Its Biomedical Applications | ||
| Egyptian Journal of Chemistry | ||
| Article 10, Volume 64, Issue 2, February 2021, Pages 661-672 PDF (684.9 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2020.45592.2930 | ||
| Authors | ||
| Hend Y.G. Mohamed1; Eman Ismael2; Mahmoud M. Elaasser3; Mostafa M.H. Khalil* 1 | ||
| 1Chemistry Department, Faculty of Science, Ain Shams University | ||
| 2Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, Egypt | ||
| 3The Regional Center for Mycology and Biotechnology, Al-Azhar University, Cairo, Egypt | ||
| Abstract | ||
| In the present study, the biosynthesis of ZnONPs utilizing Portulaca oleracea seeds aqueous extract has been reported. The reported method is a green, plant-extract mediated and low-cost approach that is capable of synthesizing ZnONPs at pH 7 with heating at 60 oC for one hour. To demonstrate the efficiency of the capping bioorganic molecules on ZnO nanoparticles, a part of the product was dried at 60 oC (denoted ZnO-60) and the other part was annealed at 500 oC (denoted ZnO-500). Both synthesized ZnONPs was crystalline in nature and hexagonal in shape with an average size of 14 nm and 34.5 nm for ZnO-60 and ZnO-500, respectively, as evidenced by XRD and TEM analysis. The synthesized nanoparticles showed high antioxidant, good antibacterial activity, which has inhibited the growth of Helicobacter pylori (ATCC 700392) and Methicillin-Resistant Staphylococcus aureus bacteria and anticancer activity for HCT-116 cells with a higher efficiency of ZnO-60 than ZnO-500. | ||
| Keywords | ||
| Biosynthesis; Zinc oxide nanoparticles; Portulaca oleracea extract; antimicrobial; antioxidant; antitumor | ||
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