Evidence of contributory role of inflammation in patients with knee osteoarthritis | ||
| SVU-International Journal of Medical Sciences | ||
| Article 2, Volume 3, Issue 1, January 2020, Pages 1-6 PDF (181.83 K) | ||
| Document Type: Original research articles | ||
| DOI: 10.21608/svuijm.2020.123716 | ||
| Authors | ||
| Nehal A. Zaki* 1; Tahia H. Saleem2; Elsayed Said3; Mohammed H. Hassan1 | ||
| 1Department of Medical Biochemistry, Faculty of Medicine, South Valley University, Qena, Egypt | ||
| 2Department of Medical Biochemistry, Faculty of Medicine, Assiut University, Assiut, Egypt | ||
| 3Department of OrthopaedicSurgery, Faculty of Medicine, South Valley University, Qena, Egypt | ||
| Abstract | ||
| Background:Osteoarthritis (OA) is a debilitating degenerative joint disease particularly affecting weightbearing joints within the body, principally the hips and knees. Objectives: We aimed to asses the inflammatory markers in the form of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) among patients with knee OA. Patients and Method: The study included 90patients with knee OA, 30 patients with mild degree of OA&30 patients with moderate degree of OA &30 patients with severe degree of OA. CRP and ESR wereperformed and analyzed for all the included patients. Results: the mean CRP of all studied patients was 5.1 ± 1.33 mg/L with minimum CRP value of 3 mg/dL and maximum one of 7 mg/dL.The mean ESR of all studied patients was 23.5 ± 2.04 mm/h with minimum ESR value of 20 mm/h and maximum one of 27 mm/h.Statistically significant difference (p= 0.028) between mild OA & severe OA groups as regard ESR, no other significant differences were observed. Conclusions:The present study confirms the presence of inflammatory state among patients with knee osteoarthritis especially those with sever form. | ||
| Keywords | ||
| CRP; ESR; knee; Osteoarthritis | ||
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