IS REPEATING THYROID SCREENING OF THE HEALTHY NEWBORN IS BENEFICIAL | ||
| Al-Azhar Journal of Pediatrics | ||
| Article 6, Volume 23, Issue 4, October 2020, Pages 1338-1355 PDF (211.66 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/azjp.2020.128815 | ||
| Abstract | ||
| Background: Some cases of congenital hypothyroidism may be missed by first neonatal screening. This study aimed to evaluate thyroid stimulating hormone TSH and free T4 of healthy full term at 7th and 28th day for detection of the missed cases of hypothyroidism at 1st neonatal screening. Methods: This prospective study was performed on 100 healthy term neonates born at Zagazig University Hospitals and Al-Azhrar Hospital. The study was done on healthy full term new born at Neonatal Intensive Care Unit of Zagazig University hospital and Al-Azhrar Hospital and was under go follow up for TSH and free T4 at 7th and 28th day of life .Newborns were classified into two groups based on their age at 7th and 28th day of life. The following was done 1. Demographic data of the studied cases. Clinical assessment, Laboratory tests: included TSH and Free T4 concentration. Results: Congenital hypothyroidism among the studied Cases at 7th day was (3%). Congenital hypothyrodism among the studied Cases at 28th day was (9%). Higher prevalence of CH among patients with positive maternal history of thyroid disorders. Higher prevalence of CH among patients delivered by cesarean section (C/S). Our results showed that history of thyroid disorders had a high risk for CH. There were statistically significant increases of maternal age among Cases with Congenital Hypothyroidism than Cases with euthyrodism. There were statistically significant decrease in weight and length among Cases with Congenital hypothyrodism than Cases with euthyrodism. Conclusion: 2nd Neonatal screening of all healthy newborns at 28th day of life is very important, since some cases of congenitl hypothyroidism can be missed in the 1st neonatal screening at the 4th day of life. | ||
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