El Demeiry, M., Emara, S., Abuleila, Y., Ali, A., Hadad, G., Abdel Salam, R. (2021). A review article on Ciprofloxacin determination with various analytical techniques.. test, 5(Chemistry), 28-32. doi: 10.21608/rpbs.2020.29710.1061
Menna Hisham El Demeiry; Samy Emara; yasmine Abuleila; Ahmed Ali; Ghada Hadad; Randa Abdel Salam. "A review article on Ciprofloxacin determination with various analytical techniques.". test, 5, Chemistry, 2021, 28-32. doi: 10.21608/rpbs.2020.29710.1061
El Demeiry, M., Emara, S., Abuleila, Y., Ali, A., Hadad, G., Abdel Salam, R. (2021). 'A review article on Ciprofloxacin determination with various analytical techniques.', test, 5(Chemistry), pp. 28-32. doi: 10.21608/rpbs.2020.29710.1061
El Demeiry, M., Emara, S., Abuleila, Y., Ali, A., Hadad, G., Abdel Salam, R. A review article on Ciprofloxacin determination with various analytical techniques.. test, 2021; 5(Chemistry): 28-32. doi: 10.21608/rpbs.2020.29710.1061

A review article on Ciprofloxacin determination with various analytical techniques.

Records of Pharmaceutical and Biomedical Sciences
Article 7, Volume 5, Chemistry - Serial Number 1, January 2021, Pages 28-32    PDF (536.63 K)
Document Type: Mini-reviews
DOI: 10.21608/rpbs.2020.29710.1061
Authors
Menna Hisham El Demeiry* 1; Samy Emara2; yasmine Abuleila3; Ahmed Ali3; Ghada Hadad4; Randa Abdel Salam5
1Pharmaceutical analytical chemistry, faculty of pharmacy, Misr International University, Cairo, Egypt
2Faculty of Pharmacy - MIU University
3Faculty of pharmacy - Misr International University
4Faculty of pharmacy, Suez Canal University, Ismailia, Egypt.
5faculty of pharmacy, Suez Canal University,Ismailia, Egypt
Abstract
Ciprofloxacin belongs to the fluoroquinolone family, which exhibits biological activity against both gram-positive and gram-negative bacteria. The previously mentioned drug is of utmost importance due to the high incidence of resistance caused by other antibiotics. Thus, numerous research studies has been conducted to determine Ciprofloxacin as well as its metabolites owing to their contribution in the drug’s biological activity. Liquid chromatography, gas chromatography, capillary electrophoresis and other separation techniques were used to develop, adapt and implement analytical techniques for the drug analysis. Other studies has made use of the hyphenation between liquid chromatography and mass spectrometry for Ciprofloxacin assay for quality control, biological fluids, animal tissues and numerous sample types. The recent advances in the ionization methods has led to the use of direct mass spectrometry techniques to analyze various sample types. This mini review aims to focus on the various analytical techniques and recent technologies implemented for Ciprofloxacin analysis.
Keywords
Ciprofloxacin; nanospray capillary; ion source; direct nano-electrospray ionization-; targeted detection
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