Assessment of Serum Level of SIRT1 in Patients with Acne Vulgaris | ||
| Benha Journal of Applied Sciences | ||
| Article 9, Volume 5, Issue 6 part (1), September 2020, Pages 63-65 PDF (656.12 K) | ||
| Document Type: Original Research Papers | ||
| DOI: 10.21608/bjas.2020.137082 | ||
| Authors | ||
| N.E. Sorour1; A.M. Hamed1; A.A. Elfallah1; D.M. Eid2 | ||
| 1Dermatology, Venereology and Andrology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt | ||
| 2Dermatology, Venereology and Andrology, Zagazig Univ., Zagazig, Egypt | ||
| Abstract | ||
| Four elements are accepted to assume a key function in the improvement of skin break out sores: abundance sebum creation, upset keratinization inside the follicle, colonization of the pilosebaceous conduit by Propionibacterium acnes, and the arrival of incendiary middle people into the skin. Point: Evaluation of serum levels of sirtuin1 (SIRT1) in skin inflammation vulgaris patients. Patients and Methods: Serum SIRT1 focuses were estimated in 30 patients with AV and 15 solid controls utilizing chemical connected immunosorbent examine (ELISA). Results: Serum SIRT1 levels are diminished in patients with serious AV contrasted with patients with gentle, moderate and controls. End: Decreased serum SIRT1 presumably mirror the part of SIRT1 in the pathogenesis of AV. | ||
| Keywords | ||
| Acne vulgaris; SIRT1; ELISA | ||
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