Elgazzar, A., Ibrahim, M., Aglan, B., Gerida, D. (2020). Evaluation of Cholesterol and c-Reactive Protein as Prognostic Factors for Survival in Critically Ill Patients. test, 5(Issue 6 part (2)), 205-209. doi: 10.21608/bjas.2020.137155
A.G. Elgazzar; M.E. Ibrahim; B.M. Aglan; D.A. Gerida. "Evaluation of Cholesterol and c-Reactive Protein as Prognostic Factors for Survival in Critically Ill Patients". test, 5, Issue 6 part (2), 2020, 205-209. doi: 10.21608/bjas.2020.137155
Elgazzar, A., Ibrahim, M., Aglan, B., Gerida, D. (2020). 'Evaluation of Cholesterol and c-Reactive Protein as Prognostic Factors for Survival in Critically Ill Patients', test, 5(Issue 6 part (2)), pp. 205-209. doi: 10.21608/bjas.2020.137155
Elgazzar, A., Ibrahim, M., Aglan, B., Gerida, D. Evaluation of Cholesterol and c-Reactive Protein as Prognostic Factors for Survival in Critically Ill Patients. test, 2020; 5(Issue 6 part (2)): 205-209. doi: 10.21608/bjas.2020.137155

Evaluation of Cholesterol and c-Reactive Protein as Prognostic Factors for Survival in Critically Ill Patients

Benha Journal of Applied Sciences
Article 8, Volume 5, Issue 6 part (2), September 2020, Pages 205-209    PDF (437.42 K)
Document Type: Original Research Papers
DOI: 10.21608/bjas.2020.137155
Authors
A.G. Elgazzar1; M.E. Ibrahim2; B.M. Aglan3; D.A. Gerida4
1Chest Dept., Faculty of Medicine, Benha Univ., Benha, Egypt
2Internal Medicine Dept., Faculty of Medicine, Benha Univ., Benha, Egypt
3Cardiothoracic Surgery Dept., Faculty of Medicine, Benha Univ., Benha, Egypt
4Critical Care Dept., Faculty of Medicine, Benha Univ., Benha, Egypt
Abstract
The aims of the study were to evaluate serum total cholesterol and serum C-reactive protein as a prognostic factor for survival in critical ill patients . The study population consisted of 50 patients (age range, 18-90 years; median, 55 years; men/women ratio, 2:3) in critical ill patients . Patients' serum levels of total cholesterol and C-reactive protein were measured upon admission to citical care unit, three days later, and on the day discharge from ICU. Total cholesterol levels were significantly lower among the non-surviving patients (day 0,115.4 ± 29.66 mg/dL; day 3,113.2 ± 37.19 mg/dL; day of discharge,104.0 ±42.96 mg/dL) than surviving patients (day 0,142.5 ± 23.93 mg/dL [P = 0.001]; day 3 ,145.5 ± 28.17 mg/dL [P = 0.001]; day of discharge 147.5 ± 35.97 mg/dL [P = 0.001]). C-reactive protein levels were significantly higher among the non-survivors (day 0,136.8 18.77 mg/dL; day 3,155.1 ± 18.94 mg/dL; day of discharge178.5 ± 22.30 mg/dL) than survivors (day 0,68.85 ±19.73 mg/dL[P = 0.001]; day 3,63.08 ± 18.05 mg/dL[P = 0.001]; day of discharge,52.98 ± 14.25 mg/dL;[P = 0.001]). Serum cholesterol and C-reactive protein can be used as markers for predicting survival in critical ill patients . Low cholesterol and high C-reactive protein levels appear as a valuable tool for individual risk assessment in critical ill patient.
Keywords
Cholesterol; C-reactive protein; Prognostic factor; Sepsis; Critical ill patient
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