EFFECT OF LOCAL ADMINISTRATION OF HYALURONIC ACID ON ORTHODONTIC TOOTH MOVEMENT IN A RABBIT MODEL | ||
| Alexandria Dental Journal | ||
| Article 1, Volume 46, Issue 1, April 2021, Pages 144-148 PDF (985.06 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/adjalexu.2020.29374.1064 | ||
| Authors | ||
| Mostafa A. Tageldin* 1; Hanan A. Ismail2; Mohamed I. Mowafy3; Afaf A. El Sawa4 | ||
| 1Department of orthodontics, Faculty of Dentistry, Alexandria University, Egypt | ||
| 2Department of Orthodontics, Faculty of Dentistry, Alexandria University, Egypt | ||
| 3Department of Orthodontics, Faculty of Dentistry, Alexandria University, Egypt. | ||
| 4Professor, Department of Oral Biology, Faculty of Dentistry, Alexandria University, Egypt | ||
| Abstract | ||
| Introduction: Using a biocompatible material to control tooth movement and enhance anchorage may be a useful method to help the orthodontist to give better treatment results. Objectives: To evaluate the effect of hyaluronic acid (HA) local injection on orthodontic tooth movement. Materials and Methods: The sample size was 15 male New Zealand rabbits. Randomized prospective split mouth trial was conducted on each rabbit. A mesializing force was applied in both sides for 21 days. Group A (control): Saline was injected on day 0. Group B: HA 1% was injected. Tooth movements were measured on 3D models. Histological analysis of alveolar bone modeling was done at the end of the experiment. Results: The quadrant receiving HA showed less amount of tooth movement than that in the control quadrant. Local administration of HA yielded 10% less tooth movement. Histological analysis revealed less resorptive activity in the quadrant receiving HA. Conclusion: There was statistically significant reduction in orthodontic tooth movement magnitude after local HA administration as well as reduction in bone resorptive activity. | ||
| Keywords | ||
| Hyaluronic acid; Rabbits; Tooth movement | ||
| References | ||
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