Rashad, N., Sayed, S., Sherif, M., Sitohy, M. (2020). The effects of weight loss intervention program on serum leptin level, histological and molecular alterations of adipose tissue in rat model with obesity.. test, 16(1), 101-108. doi: 10.21608/blj.2020.146598
Nearmeen M. Rashad; Sally E. Sayed; Mohamed H. Sherif; Mahmoud Z. Sitohy. "The effects of weight loss intervention program on serum leptin level, histological and molecular alterations of adipose tissue in rat model with obesity.". test, 16, 1, 2020, 101-108. doi: 10.21608/blj.2020.146598
Rashad, N., Sayed, S., Sherif, M., Sitohy, M. (2020). 'The effects of weight loss intervention program on serum leptin level, histological and molecular alterations of adipose tissue in rat model with obesity.', test, 16(1), pp. 101-108. doi: 10.21608/blj.2020.146598
Rashad, N., Sayed, S., Sherif, M., Sitohy, M. The effects of weight loss intervention program on serum leptin level, histological and molecular alterations of adipose tissue in rat model with obesity.. test, 2020; 16(1): 101-108. doi: 10.21608/blj.2020.146598

The effects of weight loss intervention program on serum leptin level, histological and molecular alterations of adipose tissue in rat model with obesity.

Biochemistry Letters
Article 8, Volume 16, Issue 1, 2020, Pages 101-108    PDF (319.24 K)
Document Type: Original Article
DOI: 10.21608/blj.2020.146598
Authors
Nearmeen M. Rashad1; Sally E. Sayed2; Mohamed H. Sherif3; Mahmoud Z. Sitohy4
1Internal Medicine Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
2Biochemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt
3Organic Chemistry Department, Faculty of Science Zagazig University, Zagazig, Egypt.
4Biochemistry Department, Faculty of Agriculture, Zagazig University, Zagazig Egypt.
Abstract
Background: Obesity is a resilient and complex chronic disease.
Leptin is an adipocyte-derived hormone acts as a key regulator of feeding and energy expenditure.
The aim of our study was to assess the level of serum leptin as well as leptin immuno-histochemistry expression in adipose tissue in obese and non-obese rats.
Leptin was markedly detected in young preadipocytes during lipogenesis (before weight loss (regime) in contrast to adipocytes undergoing lipolysis (after weight loss (regime) in the later weak positive.
 
 
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