Endoscopic Ultrasound (EUS) Elastography and Contrast EnhancedEUS for Discrimination of Pancreatic Masses | ||
| The Medical Journal of Cairo University | ||
| Article 22, Volume 89, March, March 2021, Pages 181-187 PDF (775.1 K) | ||
| DOI: 10.21608/mjcu.2021.153785 | ||
| Authors | ||
| MOSTAFA IBRAHIM, M.D.; DINA HAMZAWY, M.Sc.; AYMAN ABD EL-RAHIM, M.D.; AHMED ABDEL FATTAH, M.D.; NAGLAA ZAYED, M.D. | ||
| Theodor Bilharz Research Institute* and Tropical Medicine Department, Faculty of Medicine, Cairo University**, Cairo, Egypt | ||
| Abstract | ||
| AbstractBackground: Investigate the clinical utility of contrast-enhanced endoscopic ultrasound (CEEUS) and endoscopicultrasound elastography (EUS-E) in diagnosis of pancreaticmasses.Patients and Methods: 30 patients with solid pancreaticfocal lesions were included. All patients were subjected tolaboratory investigations, conventional ultrasound, triphasiccomputed tomography (CT) scan, EUS-E, CEEUS, and EUSFNA. Diagnostic accuracy of EUS-E and CEEUS were com-pared and correlated to the pathology for pancreatic lesions.Results: Malignant lesions were larger in size (32.2±10.3), and had greater SR-E-EUS and more hypovascular pattern. The mean strain ratio was 16.4±8.14 for benign and 67.76 ± 72.45 for malignant lesions (p=0.001). Hypovascular pattern after contrast injection was present in 76% of malignant and 60% of benign lesions (p=0.66). ROC analysis for the mean SR-E-EUS of the region of interest yielded an optimal cutoff of 74.4 with an AUC of 0.91 (95% CI: 0.74-0.98) for the best power distinction for malignancy. It provided a sensitivity and specificity of 75% and 80%, respectively.Conclusion: EUS based novel modalities (CE-EUS andEUS-E) could distinguish between benign and malignantlesions and improve the identification of the vascular patternrespectively. Both techniques could be considered a comple-mentary imaging modality in the characterization of pancreatictumors. | ||
| Keywords | ||
| Contrast-enhanced ultrasound; Endoscopicultrasound elastography | ||
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