Ali, D., Abd EL-moktader, A., Abd-El Baky, R., Hussein, S. (2021). The Relation Between Neonatal Vitamin D deficiency and Early Onset Sepsis in Term Infants. test, 2(2), 361-371. doi: 10.21608/mid.2021.63684.1125
Doaa Y. Ali; Ahmed M. Abd EL-moktader; Riham Makhlof Abd-El Baky; Sherin Khamis Hussein. "The Relation Between Neonatal Vitamin D deficiency and Early Onset Sepsis in Term Infants". test, 2, 2, 2021, 361-371. doi: 10.21608/mid.2021.63684.1125
Ali, D., Abd EL-moktader, A., Abd-El Baky, R., Hussein, S. (2021). 'The Relation Between Neonatal Vitamin D deficiency and Early Onset Sepsis in Term Infants', test, 2(2), pp. 361-371. doi: 10.21608/mid.2021.63684.1125
Ali, D., Abd EL-moktader, A., Abd-El Baky, R., Hussein, S. The Relation Between Neonatal Vitamin D deficiency and Early Onset Sepsis in Term Infants. test, 2021; 2(2): 361-371. doi: 10.21608/mid.2021.63684.1125

The Relation Between Neonatal Vitamin D deficiency and Early Onset Sepsis in Term Infants

Microbes and Infectious Diseases
Article 22, Volume 2, Issue 2, May 2021, Pages 361-371    PDF (316.43 K)
Document Type: Original Article
DOI: 10.21608/mid.2021.63684.1125
Authors
Doaa Y. Ali* 1; Ahmed M. Abd EL-moktader2; Riham Makhlof Abd-El Baky3; Sherin Khamis Hussein2
1Department of Clinical and Chemical Pathology, Faculty of Medicine, Fayoum University, Al Fayoum, Egypt.
2Department of Pediatrics, Faculty of Medicine, Fayoum University, Al Fayoum, Egypt.
3Department of Pediatrics, Fayoum general hospital, Al Fayoum, Egypt.
Abstract
Abstract
Background: Vitamin D had an important influence on the innate and adaptive immune system. 25-hydroxyvitamin D (25(OH)D) serum level is known to be the best predictor of vitamin D level.
Objective is to determine the relationship between neonatal 25(OH)D level in early-onset sepsis (EOS) and its severity in term infants.
Methods: This case-control study was performed on 50 septic neonates admitted to Fayoum University Hospitals' Neonatal Intensive Care Unit as a case group, and 50 healthy neonates as a control group. Each subject was subjected to a detailed history and meticulous general & systemic examinations. Laboratory assessment in form of complete blood count with differential counts, C-reactive protein (CRP), blood culture, and serum 25(OH)D level in infants and within 72 hours of life.
Results: 25(OH)D levels in cases (4.91 ng/ml) were significantly lowered than those in controls (13.0 ng/ml) (p < /p>
Keywords
Early onset neonatal sepsis; Serum 25(OH)D level; Tem infants
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