Genetic Polymorphism of GH, IGF1 AND BMP15 Genes in Maraz Goat | ||
| Journal of Animal and Poultry Production | ||
| Article 3, Volume 11, Issue 12, December 2020, Pages 503-507 PDF (779.87 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jappmu.2020.161171 | ||
| Author | ||
| Karwan Mohammad Hama Khan* | ||
| Animal Science department, College of Agricultural Engineering Sciences, University of Sulaimani, Sulaimani City, Kurdistan Region, Iraq | ||
| Abstract | ||
| The Studies of genetic polymorphism in local animals aim at evaluating the genetic diversity of animal breeds chiefly for conservation purposes. In this research, single nucleotide polymorphism (SNP) was used to detect point mutation of GH, IGF1, BMP15 genes in Maraz goat. Forty blood samples were collected from Maraz goat, DNA was isolated and primer was used to amplify GH, IGF1, and BMP15 genes. Finally, sequencing methodology was applied for PCR products. Results of GH gene showed only one SNPs (AG) at nucleotide number 58pb. The sequence results of IGF1 illustrated two point mutations at nucleotide number 5502 and 5675 bp. While according to data sequences no point mutation was detected of BMP15 gene. These outcomes revealed that the SNP marker of the GH, IGF-I, and BMP15 genes will be a possible molecular marker for growth traits and cashmere fiber in Maraz goat. This research displays that the genetic similarities between Maraz goat and other breeds match their geographical distribution which indicates that the Maraz goat is robustly separated from the other breeds. | ||
| Keywords | ||
| GH; IGF1; BMP15; SNPs; diversity; Maraz goat | ||
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