Gross Motor Functioning in Children with Cerebral Palsy after Stem Cell Transplantation | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 64, Volume 83, Issue 1, April 2021, Pages 1215-1217 PDF (311.63 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2021.162853 | ||
| Authors | ||
| Reham S. Tarkan* 1; Mohamed Sedky2; Khaled H. Taman1; George S. Kobinia3; Maisa N. Farid1 | ||
| 1Faculty of Postgraduate Childhood Studies, Ain Shams University, Cairo, Egypt | ||
| 2Faculty Of Medicine, Misr University For science and Technology | ||
| 3Stem Cell Therapy Group Vienna Medical University of Vienna –Austria | ||
| Abstract | ||
| Background Cerebral palsy (CP) is a non-progressive motor disability that mostly results from perinatal complications. It demands extensive and multidisciplinary care, which poses a burden for patients and their families and a challenge to health systems. We aimed to evaluate the effect of stem cells transplantation on gross motor functioning of CP patients. Patients and Methods: It is a prospective study conducted on 20 children diagnosed with cerebral palsy with severe motor disability (GMFC 5) further classified into two groups according to age. The study was carried out from January 2018 to January 2020. Follow up of the patients was done before injection of stem cells and 3, 6, 9 and 12 months after injection of stem cells using Gross motor function classification scale (GMFC). Results: The study revealed that GMFC scores in pre-injection and 3,6,9and 12 months evaluations were not statistically significant when compared among the two groups while significant improvement was found in gross motor scale from pre-injection to final injection score in each group. Median GMFC changed from 5 to 2 among all cases. Conclusion: Gross motor function in children with CP remarkably improved after stem cell transplantation. | ||
| Keywords | ||
| Transplantation; Stem Cells; Gross Motor; Cerebral palsy | ||
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