Gastrointestinal Stromal tumor of the stomach and retroperitoneal paraganglioma in Saudi woman, “A case report” | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 1, Volume 46, Issue 1, January 2012, Pages 1-6 PDF (886.33 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2012.16351 | ||
| Author | ||
| Dalal Nemenqani | ||
| Department of Pathology ,College Of Medicine, Taif University , Taif, Kingdom of Saudi Arabia. | ||
| Abstract | ||
| Gastrointestinal stromal tumor (GIST) and paraganglioma are uncommon tumors; mostly occur in a sporadic and isolated form. They are occasionally components of 3 clinical syndromes, familial paraganglioma and gastric GIST, neurofibromatosis type 1 and Carney triad. The latter does not show genetic mutations and affects young women predominantly. This article reports the occurrence of GIST and retroperitoneal paraganglioma in young Saudi woman aged 22 years. The initial clinical presentation was acute severe gastric bleeding. Gastric mass with retroperitoneal mass was discovered during surgical exploration. Histological and immunohistochemical study of both masses showed features of GIST and paraganglioma. The combination of GIST and retroperitoneal paraganglioma in the reported case may be incomplete expression of Carney triad or be coincidental occurrence. | ||
| Keywords | ||
| Gastric GIST; Retroperitoneal paraganglioma; Carney triad; Immunohistochemistry | ||
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