Antimicrobial Activities of Seed and Leaf Extracts of Moringa oleifera against Common Clinical Microbial Isolates | ||
| Egyptian Academic Journal of Biological Sciences, G. Microbiology | ||
| Article 5, Volume 7, Issue 1, December 2015, Pages 47-52 PDF (141.57 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/eajbsg.2015.16484 | ||
| Authors | ||
| Olaitan J. O.1; Kareem S. O.2; Aroyehun D. B.2; Omeike S. O.2 | ||
| 1Department of Biological Science, Osun State University, PMB 4494, Osogbo, Osun State, Nigeria | ||
| 2Department of Microbiology, Federal University of Agriculture, PMB 2240, Abeokuta, Ogun State, Nigeria | ||
| Abstract | ||
| Seed and leaf extracts of Moringa oleifera were tested against selected bacterial and fungal pathogens of clinical importance comparing aqueous and ethylacetate efficacy as solvents of extraction. Agar disc and agar well diffusion methods were employed for the tested bacteria and fungi respectively. While the bacteria included Staphylococcus aureus, Streptococcus pneumonia, Escherichia coli, Klebsiella pneumonia, Pseudomonas aeruginosa and Salmonella typhi, the fungal species were Candida albicans, Aspergillus niger and A. flavus. The in vitro bioassay revealed that the ethylacetate seed extracts showed better activity compared to the aqueous extracts, with the highest effectivenessobserved in ethylacetate extract against E. coli (23mm) and lowest in aqueous extract against A. flavus (6 mm). Conclusively, plant parts extracted with ethylacetate proved to possess more antimicrobial activities than aqueous, thereby suggesting ethylacetate as an effective solvent in the extraction of active phytochemical compounds. | ||
| Keywords | ||
| Moringa Olifera; Extracting solvents Microbial pathogens Minimum inhibitory concentration | ||
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