Antimicrobial Compound Isolated From The Plant Pothos scandens L. | ||
| Egyptian Journal of Chemistry | ||
| Article 9, Volume 64, Issue 9, September 2021, Pages 4803-4807 PDF (215.62 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2021.56540.3216 | ||
| Authors | ||
| Deepjyoti Dutta1, 2; Manob Bordoloi1; Nayan Bhattacharyya* 2 | ||
| 1Chemical Science and Technology Division, CSIR-North East Institute of Science & Technology, Jorhat 785006, Assam, India | ||
| 2Department of Chemistry, Sikkim Manipal University (Sikkim Manipal Institute of Technology), Majitar 737136, Sikkim, India | ||
| Abstract | ||
| Abstract Pothos scandens L. is a medicinal plant found in North East India with various ethno-medicinal activities. A compound was isolated from the bark of P. scandens and the structure was characterized as Octyl isonicotinate (1) by extensive NMR, FT-IR and mass analysis. Compound 1 exhibited significant antimicrobial activity against Escherichia coli and Candida albicans by Agar well diffusion method with zone of inhibition value of 9.16±0.28 mm and 12.5±0.51 mm, respectively compared with standard Amikacin (19.33±0.57) and Fluconazole (15.9± 0.12). The minimum inhibitory concentration (MIC) values were found 12.30 µg/mL and 6.50 µg/mL respectively as compared to Amikacin (4.37 µg/mL) and Fluconazole (7.5µg/mL). | ||
| Keywords | ||
| Pothos scandens; Octyl isonicotinate; antimicrobial | ||
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