Clinical, Laboratory and Radiological Predictors of Unfavorable Hospital Admission Course for Diabetic Patients with COVID-19 | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 80, Volume 83, Issue 1, April 2021, Pages 1321-1329 PDF (402.95 K) | ||
| DOI: 10.21608/ejhm.2021.165528 | ||
| Authors | ||
| Mohamed Sorour Mohamed1; Tamer M. Gouda1; Amr Shaaban Hanafy1; Hussein Mohammed Hussein1; Ali M. Hassanin2; Nahla Ibrahim Zidan3; Walaa Sabry Fouad4 | ||
| 1Departments of Internal Medicine Faculty of Medicine, Zagazig University Hospital, Egypt. | ||
| 2Departments of Radiodiagnosis, Faculty of Medicine, Zagazig University Hospital, Egypt. | ||
| 3Departments of 3Clinical Pathology, Faculty of Medicine, Zagazig University Hospital, Egypt. | ||
| 4Departments of Family Medicine, Faculty of Medicine, Zagazig University Hospital, Egypt. | ||
| Abstract | ||
| Background: Patients with diabetes mellitus infected with the new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are at risk of high morbidity and mortality. Objective: Our study aimed to address the clinical, laboratory and radiological predictors of hospital admission course for patients with diabetes mellitus with COVID19 infection at the time of admission. Patients and Methods: This was a single center, retrospective study of patients with diabetes mellitus (DM) admitted with COVID-19 infection. Patients with unfavorable admission course were compared with those of favorable course regarding patient characteristics, clinical presentation, results of laboratory investigations and chest CT severity score. Univariate and multivariate analysis associated with the unfavorable course was performed. Results: Among 141 patients with DM admitted with COVID19, 44 patients had unfavorable course. Those with the favorable course were significantly younger (53.3±16.4) vs (67.3 ±15.8) in the unfavorable course group, multivariate analysis revealed that age more than 65, presence of hypertension, CT severity scoring, high HBA1c, AST, IL6, oxygen saturation less than 93% and low lymphocyte count were the independent predictors of the unfavorable hospital admission course. Conclusions: Our finding suggests that old age, presence of hypertension, hypoxia at presentation, in addition to high HBA1c, AST, IL6, CT severity scoring and low lymphocyte count were significant predictors of unfavorable admission course in COVID19 patients with diabetes. | ||
| Keywords | ||
| Coronavirus; COVID19; Diabetes mellitus; Predictors; Prognosis | ||
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