Comparison between Haemagglutination Inhibition and Complement Fixation Tests in Detecting Antibodies Responses Following Influenza Viral Infection | ||
| Egyptian Academic Journal of Biological Sciences, G. Microbiology | ||
| Article 5, Volume 4, Issue 1, December 2012, Pages 35-38 PDF (143.33 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/eajbsg.2012.16658 | ||
| Author | ||
| Muthana A.K. Al-zobaei | ||
| Medical Microbiology, Microbiol. Dept. Virology, College of Medicine, Univ. Anbar | ||
| Abstract | ||
| Objectives: To evaluate sensitivity and specificity of HI and CF tests for detecting antibody responses following naturally occurring influenza A and B infections. Methods: One hundred and twenty blood samples were drawn from one hundred patients with flue-like illness and twenty apparently healthy control subjects and tested at Central Health Laboratory in Baghdad/ Iraq using HI and CF tests for detecting three currently circulating influenza A and B strains during the period from the 1st of January 2008 to the 1st of June 2009. Results: 78-80% of the patients with flu-like illness responded to a t least one of three influenza virus antigens as measured by HI, while 34-35% of those patients showed a response by CF test. Conclusions: HI test has a higher sensitivity and lower specificity than CF test for detecting antibody responses from patients with influenza A and B viral infections. | ||
| Keywords | ||
| Influenza viruses; HI; CF; Influenza serology | ||
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