Ekici, A., Timuçin, D., Gürbüz, E., Ünlü, A., Aydemir, S., Yilmaz, H. (2021). Investigation of the relationship between schizophrenia and toxoplasmosis in Van province, Turkey. test, 14(1), 34-38. doi: 10.21608/puj.2021.49914.1093
Abdurrahman Ekici; Damla Timuçin; Esra Gürbüz; Ahmet Ünlü; Selahattin Aydemir; Hasan Yilmaz. "Investigation of the relationship between schizophrenia and toxoplasmosis in Van province, Turkey". test, 14, 1, 2021, 34-38. doi: 10.21608/puj.2021.49914.1093
Ekici, A., Timuçin, D., Gürbüz, E., Ünlü, A., Aydemir, S., Yilmaz, H. (2021). 'Investigation of the relationship between schizophrenia and toxoplasmosis in Van province, Turkey', test, 14(1), pp. 34-38. doi: 10.21608/puj.2021.49914.1093
Ekici, A., Timuçin, D., Gürbüz, E., Ünlü, A., Aydemir, S., Yilmaz, H. Investigation of the relationship between schizophrenia and toxoplasmosis in Van province, Turkey. test, 2021; 14(1): 34-38. doi: 10.21608/puj.2021.49914.1093

Investigation of the relationship between schizophrenia and toxoplasmosis in Van province, Turkey

Parasitologists United Journal
Article 6, Volume 14, Issue 1, April 2021, Pages 34-38    PDF (321.08 K)
Document Type: Original Article
DOI: 10.21608/puj.2021.49914.1093
Authors
Abdurrahman Ekici* 1; Damla Timuçin2; Esra Gürbüz3; Ahmet Ünlü4; Selahattin Aydemir1; Hasan Yilmaz1
1Departments of Parasitology, Van Yüzüncü Yıl University, Faculty of Medicine
2SBÜ􀇆 Van Training and Research Hospital for Mental and Neurological Diseases
3SBÜ􀇆 Van Training and Research Hospital for Mental and Infectious Diseases and Clinical Microbiology
4SBÜ􀇆 Van Training and Research Hospital for Mental and , Van Yüzüncü Yıl University, Gevaş Vocational School ,Van, Turkey
Abstract
Background: Schizophrenia is a worldwide, serious neuropsychiatric disorder of unknown cause.
Previous studies showed that infectious agents may play a role in its etiology. Among them, T. gondii was
strongly hypothesized.
Objectives: The aim of this study was to determine the IgG and IgM seroprevalence of T. gondii in
schizophrenia patients.
Subjects and Methods: The study was conducted on 190 patients diagnosed with schizophrenia in Van
province, Turkey. Also included as the control group were 100 healthy individuals. Anti-T. gondii IgG
and IgM antibody positivity was determined by enzyme-linked immunosorbent assay (ELISA) in blood
samples taken from both groups.
Results: Anti-T. gondii IgG antibody was detected in 120 schizophrenic patients (63.2%), and in 100
(29%) healthy controls. Anti-T. gondii IgM antibody seropositivity was not detected in either group.
Conclusion: In line with the data obtained in the study carried out in Van province, it was concluded
that individuals infected with T. gondii were more likely to develop schizophrenia. Further studies are
recommended to prove the relationship between T. gondii and schizophrenia.
Keywords
Schizophrenia; toxoplasmosis; Toxoplasma gondii; Van
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