Cutaneous infections among Human Immunodeficiency Virus (HIV) - infected patients in a single center in Kuala Lumpur, Malaysia | ||
| Microbes and Infectious Diseases | ||
| Article 7, Volume 3, Issue 1, February 2022, Pages 55-61 PDF (244.34 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mid.2021.71180.1140 | ||
| Authors | ||
| Ahlam Mutahar Muthanna* 1; Adawiyah Jamil2 | ||
| 1Dermatology, Faculty of Medicine, The National University of Malaysia, Kuala Lumpur, Malaysia | ||
| 2Professor, Dermatology Department, Faculty of Medicine, The National University of Malayisa, Kuala Lumpur, Malaysia | ||
| Abstract | ||
| Background: Human immunodeficiency virus (HIV) infection is frequently associated with cutaneous infections. Objective: To determine the spectrum of dermatological infections among HIV positive patients, identify the causative microorganisms and CD4 count. Methods: This is a retrospective study conducted in a tertiary center. HIV-positive patients registered in 2013 to 2018 were identified from casemix database, those with suspected cutaneous infection were selected. Data was obtained from electronic and physical medical records. Results: A total of 27 patients were enrolled. Mean age was 38.61±11 years, 22(81.5%) were males and 5(18.5%) were females. Most patients 14(52%) developed more than one skin disease, there were a total of 46 diagnoses. The skin infections were fungal 11(24%), viral 4(8.7%) and bacterial 4(8.7%). Disseminated mycoses were mostly due to Penicillium marneffei 4(8.7%). Superficial fungal infections were due to Fusarium sp, Candida sp and Trichosporum sp < /em>. Cutaneus candidiasis constituted 3(6.47%). The average CD4 count in patients with fungal infections was 79 cells/mm3. Other skin diseases documented were adverse cutaneous drug reactions 8(17.4%) and pruritic papular eruption 5(11%). CD4 count was Conclusion: Both disseminated and superficial fungal infections were common in our cohort. Penicillium marneffei caused majority of disseminated infections while superficial infections are due to moulds. | ||
| Keywords | ||
| Human immunodeficiency virus; acquired immunodeficiency syndrome; skin; infection | ||
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