Short Letrozole Therapy Versus Extended (Long) Letrozole Therapy For Induction of Ovulation in Women With Polycystic Ovary Syndrome. Randomised study | ||
| Benha Journal of Applied Sciences | ||
| Article 39, Volume 6, Issue 2, March and April 2021, Pages 243-253 PDF (410.61 K) | ||
| Document Type: Original Research Papers | ||
| DOI: 10.21608/bjas.2021.169459 | ||
| Authors | ||
| K.M. Salama; B.E. Sakr; S.A. Azab | ||
| Obstetrics and gynecology, Dept.,Faculty of Medicine, Benha Univ., Benha, Egypt | ||
| Abstract | ||
| Presentation: Polycystic Ovary Syndrome is quite possibly the most well-known reasons for anovulatory fruitlessness, influencing 8-13% of conceptive matured ladies . It is by a long shot the most well-known reason for hyperandrogenic anovulatory fruitlessness and was depicted the greater part a century prior, the basic reason for this issue is as yet dubious . Point: to examine the viability of short(2.5mg day by day for 5 days) versus broadened course (2.5mg day by day for 10 days) of letrozole treatment for ovulation acceptance in ladies with polycystic ovary syndrome.Subject &Method: This examination directed on (40) patients with PCOS They were arbitrarily assigned in two gatherings. Gathering 1 (20 patients )got letrozole in adose of 5mg for 5 days while the gathering 2 (20 patients) got letrozole in adose of 2.5 mg for 10 days.Result : The all out number of follicles in the present moment letrozole was 3±1 while it was 4±1 in the long letrozole bunch. In our examination the endometrial thickness was 8±2 in both short and long letrozole bunch .The pregnancy rate was 15% in short letrozole bunch while it was 25% in long letrozole bunch . End: The long letrozole treatment (2.5mg for 10 days) can create more develop follicles and in this manner a greater number of pregnancies than the short letrozole treatment (5mg for 5 days). | ||
| Keywords | ||
| PCOS; Letrozole | ||
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