THE EFFECTS OF EXPOSURE TO ORGANOPHOSPHOROUS COMPOUNDS ON SOME ASPECTS OF CARBOHYDRATE METABOLISM IN Tilapia zillii | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 9, Volume 39, Issue 1, April 2018, Pages 223-228 PDF (193.86 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2018.16966 | ||
| Authors | ||
| Abdel-Salam Mohamed Ibraik Ohaida1; Nuha Mahmoud A. Akrawee2 | ||
| 1Zoology Department. Faculty of Science. University of 7 October Misurata | ||
| 2High Institute of Medical Technology, Misurata | ||
| Abstract | ||
| The Effect of organophosphorous insecticides compounds (Malathion and Fenitrothion) on certain aspects of carbohydrate metabolism in the freshwater fish Tilapia zillii exposed to 1/3 LC50 of both insecticides for 96 hours was studied. Organophosphorous compounds were found to affect some parameters of carbohydrate metabolism. Muscle and liver glycogen decreased significantly accompanied with significant increase of the plasma glucose and the specific activity of phosphorylase enzyme in both liver and muscles. The activity of Succinate dehydrogenase (SDH), lactate dehydrogenase (LDH) and malate dehydrogenase (MDH) showed a significant decrease in liver and muscle tissues. Alanine transferase (ALT) and Aspartate transferase (AST) in liver and muscles also showed a significant decrease. Significant alterations in the content of metabolites and enzyme activity under malathion and fenitrothion toxicity seemed to suggest marked shift from aerobic to anaerobic condition. | ||
|
Statistics Article View: 167 PDF Download: 434 |
||
