PYRROLIZIDINE ALKALOIDS OF CERINTHE GLABRA MILLER (BORAGINACEAE) | ||
| Zagazig Journal of Pharmaceutical Sciences | ||
| Article 1, Volume 13, Issue 1, June 2004, Pages 1-5 PDF (2.36 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zjps.2004.169693 | ||
| Author | ||
| Assem El-Shazly* | ||
| Department of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt | ||
| Abstract | ||
| The pyrrolizidine alkaloids of Cerinthe glabra Miller (total yield 0.3 mg/g dry weight) was investigated by capillary GLC and GLC-MS in combination with retention indices. Six pyrrolizidine alkaloids were identified for the first time in this plant, of which 5 unambiguously identified by comparing their specific retention indices and mass fragmentation with those of authentic alkaloids and literature data. Lycopsamine, 7-acetyllycopsamine and 3'-acetyllycopsamine were the prominent alkaloids in the reduced extract, Supinine, 3,7-diacetyllycopsamine and the tentatively identified 7-hydroxymethylbutyryl-9-viridifloryl-retronecine were detected as minor constituents. | ||
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