Abdel-Aal, M., Ghareib, S. (2003). CHEMICAL COMPOSITION AND ANTI-INFLAMMATORY ACTIVITY OF VERBENA SUPINA L ; GROWING IN EGYPT. test, 12(1), 1-8. doi: 10.21608/zjps.2003.169695
Mahmoud Abdel-Aal; Salah Ghareib. "CHEMICAL COMPOSITION AND ANTI-INFLAMMATORY ACTIVITY OF VERBENA SUPINA L ; GROWING IN EGYPT". test, 12, 1, 2003, 1-8. doi: 10.21608/zjps.2003.169695
Abdel-Aal, M., Ghareib, S. (2003). 'CHEMICAL COMPOSITION AND ANTI-INFLAMMATORY ACTIVITY OF VERBENA SUPINA L ; GROWING IN EGYPT', test, 12(1), pp. 1-8. doi: 10.21608/zjps.2003.169695
Abdel-Aal, M., Ghareib, S. CHEMICAL COMPOSITION AND ANTI-INFLAMMATORY ACTIVITY OF VERBENA SUPINA L ; GROWING IN EGYPT. test, 2003; 12(1): 1-8. doi: 10.21608/zjps.2003.169695

CHEMICAL COMPOSITION AND ANTI-INFLAMMATORY ACTIVITY OF VERBENA SUPINA L ; GROWING IN EGYPT

Zagazig Journal of Pharmaceutical Sciences
Article 1, Volume 12, Issue 1, June 2003, Pages 1-8    PDF (3.84 M)
Document Type: Original Article
DOI: 10.21608/zjps.2003.169695
Authors
Mahmoud Abdel-Aal* 1; Salah Ghareib2
1Department of Pharmacognosy, Faculty of Pharmacy, Zagazig University,Zagazig, Egypt
2Department of Pharmacology, Faculty of Pharmacy, Zagazig University,Zagazig, Egypt
Abstract
Phytochemical investigation of the chloroform extract of Verbena supina L. afforded ursolic acid, oleanolic acid, 3β, 24-dihydroxy-urs-12-en-28-oic acid and 3 β,24-dihydroxy-olean-12-en-28-oicacid.The ethyl acetate extract yielded the pheny1propanoid acteoside. The isolated materials were identified on the bases of chromatographic spectroscopic (UV, JR, 1H and 13C-NMR and MS) evidences. Chloroform extract, ursolic acid and 3β,24-dihydroxy-urs-12-en-28-oic acid exhibited potent anti-inflammatory activities in comparison with hydrocortisone using carrageenan- induced hind paw edema model.
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