Synthesis of and characterization of some Heterocyclic Compounds derived from Thiophenol | ||
| Egyptian Journal of Chemistry | ||
| Article 26, Volume 64, Issue 10, October 2021, Pages 5655-5662 PDF (653.38 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2021.70759.3559 | ||
| Author | ||
| Shaima Ibraheem Chyad AL-Khazraji* | ||
| Department of Chemistry, College of Education for Pure Sciences, University of Kirkuk, Kirkuk, Iraq | ||
| Abstract | ||
| This research work involved preparation of heterogeneous pent lateral cyclic compounds (thiazolidine -4- one, benzothiazole, triazole, 4-oxothiazolidin) using thiophenol as raw materials: Thiophenol was reacted with mono chloroacetic acid in the presence of potassium hydroxide to prepare (sh1) followed by ortho amino aniline results the (sh2). The reaction of thiophenol with ethylchloroacetate afforded (sh3) and the reaction of (sh3) with thiosemicarbazide and 4% NaOH leads to ring closure giving 1,2,4- triazole (sh5). A treatment of thiophenol with hydrazine hydrate to obtain the intermediate (sh6) with aromatic aldehyde synthesized azomethines (sh7- sh9) then treated with mercaptoacetic acid to obtained (sh10-sh12). A treatment of thiophenol with chloroacetyl chloride produced (sh13) compound then treated with hydrazine hydrate to obtain (sh14) compound followed by bromobenzaldehyde synthesized azomethine (sh15) compound then treated with mercaptoacetic acid to obtained (sh16) compound. Characterization results for the prepared compounds using IR spectroscopy, NMR and melting points confirmed their chemical structures. | ||
| Keywords | ||
| Thiophenol; Thiophenol derivatives; triazole; 4-oxothiazolidin; benzothiazol | ||
|
Statistics Article View: 870 PDF Download: 520 |
||
