Electron Microscopic study of Desmosomes and Tonofilaments in Lichen Planus | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 7, Volume 28, Issue 1, July 2007, Pages 363-370 PDF (913.22 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2007.17668 | ||
| Authors | ||
| Sawsan Khalifa EL- Sayed1; Hossam El- Dein Hussin Osman2 | ||
| 1Department of Dermatology and Venereology, Al- Azhar University for Girl, Cairo | ||
| 2Anatomy Department, Al- Azhar University for Boys, Cairo | ||
| Abstract | ||
| Introduction: Lichen planus (L.P) is an idiopathic inflammatory disease of the skin and mucous membrane. Desmosomes are responsible for the adhesion of keratinocytes. Tonofilaments are one of the major cytoskeleton structure in mammalian epidermis. Patients and Methods: Six patients complained from Lichen planus are included in this study for the study of ultrastructure of both desmosomes & tonofilaments . Results: revealed an increase in the size and numbers of both of them which can be explained as a one of the defensive mechanism of the cells against frequent rubbing which is accompanied L.P. which is considered as a resistance mechanism of keratinocytes. | ||
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