Acute Salt Toxicity Caused by Whey Ingestion in Mixed-breed 6-months old Puppy: A case study | ||
| Journal of Applied Veterinary Sciences | ||
| Article 5, Volume 6, Issue 3, July 2021, Pages 31-37 PDF (762.31 K) | ||
| Document Type: Case Study | ||
| DOI: 10.21608/javs.2021.77045.1081 | ||
| Authors | ||
| Erdem GÜLERSOY* 1; Süleyman Serhat İYİGÜN2 | ||
| 1Department of Internal Medicine, Faculty of Veterinary Medicine, Harran University, Şanlıurfa, Turkey. | ||
| 2Department of Internal Medicine, Faculty of Veterinary Medicine, Selçuk University, Konya, Turkey. | ||
| Abstract | ||
| This case report aims to emphasize the acute management of a dog with suspected salt intoxication, which consists of a treatment protocol with hematological and Modified Glasgow Coma Scale (MGCS) changes and electrocardiographic (ECG) evaluation. A 6-month-old male mixed-breed dog was admitted to the emergency clinic with complaints of weakness, hypersalivation, vomiting, diarrhea and gait disturbance. It was learned from the owner that the dog was fed on whey for the first time on the morning of the admission day. Salt toxication was suspected based on history and clinical symptoms. The diagnosis was confirmed by laboratory analysis (pH: 7.185, Na: 178 mmol./L, Cl: 155 mmol./L, K: 8.3 mmol./L, HCO3: 16.1 mmol./L, BE: -8.8 mmol./L, BUN: 105.7 mg/dl, creatinine: 5.4 mg/dl, AST: 513 U/L, amylase: 2324 U/L, LDH: 794 U/L, calcium: 11.8 mg/dl, phosphorus: 13.9 mg/dl, cholesterol: 515 mg/dl, magnesium: 3.6 mg/dl, GGT: 62 U/L CPK: 450 U/L and CK-MB: 324.5 U/L), ECG (sinus tachycardia (180 bpm) and mild ST depression) and MGCS evaluation (pre-treatment score; 7, grave). A treatment protocol including fluid therapy, antiemetic, diuretic, anticonvulsant, beta-blocker to prevent sodium retention and oxygen therapy was administrated to the dog during the hospitalization period. It was observed that the clinical findings and MGCS score improved and some blood parameters returned to their reference range on Day 2. Since the dog died on Day 3 after the hospitalization period, which was terminated at the owner's request, it was concluded that an adequate hospitalization period is important. The presented treatment protocol with MGCS evaluation in salt toxicity was successful enough only in acute management. | ||
| Keywords | ||
| Dog; fluid therapy; hypernatremia; modified Glasgow coma scale; salt toxicity | ||
| References | ||
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AL-ABSI, A., GOSMANOVA, E. O., WALL, B. M., 2012. A clinical approach to the treatment of chronic hypernatremia. Am J Kidney Dis, 60, 1032–1038. ALSHAYEB, H. M., SHOWKAT, A., BABAR, F., 2011. Severe hypernatremia correction rate and mortality in hospitalized patients. Am JMed Sci, 341, 356–60. ANGELOS, S. M., VAN METRE, D. C., 1999. Treatment of sodium balance disorders. Veterinary clinics of North America. Food Animal Practice, 15, 587–607. ARAMBEWELA, M. H., SOMASUNDARAM, N. P., GARUSINGHE, C., 2016. Extreme hypernatremia as a probable cause of fatal arrhythmia: a case report. J Med Case Rep, 10, 272. BAGLEY, R. S., LAHUNTA, A. D., RANDOLPH, J. F., 1993. Hypernatremia, adipsia, and diabetes insipidus in a dog with hypothalamic dysplasia, Journal of American Animal Hospital Association, 29, 267-271. BEYNEN, A. C., 2017. Salt in dog foods. Creature Companion, 10, 34-35. BLASCHEK, K. M., WENDORFF, W. L., RANKIN, S., 2007. Survey of salty and sweet whey composition from various cheese plants in Wisconsin. Journal of dairy science, 90, 2029-2034. BOWINS, B., 2018. The rational unconscious: Implications for mental illness and psychotherapy. Am J Psychother, 71, 28-38. BRAUN, M. M., BARSTOW, C. H., PYZOCHA, N. J., 2015. Diagnosing and management of sodium disorders: Hyponatremia and hypernatremia. Am Fam Physician, 91, 299–307. DIBARTOLA, S. P., 2006. Disorders of sodium and water: hypernatremia and hyponatremia. In Fluid. 47-80. In: SP Dibartola (Ed), Electrolyte and Acid-Base Disorders in Small Animal Practice (3rd ed). St Louis MO, Saunders Elsevier. FISHER, L. A., KO, N., MISS, J., 2006. Hypernatremia predicts adverse cardiovascular and neurological after SAH. Neurocrit Care, 5, 180–185. KAZANJI, N., ASSAD, W. A., GJEORGJIVESKI, M., 2015. Extreme hypernatremia (254 mmol/l) and electrocardiogram findings. Int Urol Nephrol, 47, 871–872. KIM, M. K., LOPETCHARAT, K., GERARD, P. D., 2012. Consumer awareness of salt and sodium reduction and sodium labeling. J Food Sci, 77, 307-313. LUMSDEN, J. H., MULLEN, K., McSHERRY, B. J., 1979. Canine Hematology and Biochemistry Reference Values. Can J Comp Med, 43, 125-131. MORRIS, M., PATTON, R., TEETER, S., 1976. Low sodium diet in heart disease: how low is low? Veterinary Medicine, 71: 1225-1227. PLATT, S. R., RADAELLI, S. T., MCDONNELL, J. J., 2001. The prognostic value of the modified Glasgow coma scale in head trauma in dogs. Journal of veterinary internal medicine / American College of Veterinary Internal Medicine, 15, 581-584. POUZOT, C., DESCONE‐JUNOT, C., LOUP, J., 2007. Successful treatment of severe salt intoxication in a dog. Journal of Veterinary Emergency and Critical Care, 17, 294-298. SMITH, S. T., METZGER, L., DRAKE, M. A., 2016. Evaluation of whey, milk, and delactosed permeates as salt substitutes. J. Dairy Sci. 99, 8687-8698. TITZE, J., RITZ, E., 2009. Salt and its effect on blood pressure and target organ damage: new pieces in an old puzzle. Journal of Nephrology, 22, 177-189.
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