Effect Of Some Herbal Medicine On Some biochemical paramcters In Diabetic Rats | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 9, Volume 22, Issue 1, January 2006, Pages 98-110 PDF (353.46 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2006.18032 | ||
| Authors | ||
| Eman G.E. Helal1; Mervat A. Abbas2 | ||
| 1Department of Zoology, Faculty of science (Girls) Faculty of Medicine for Girls Al Azhar University. | ||
| 2Department of Biochemistry Faculty of Medicine for Girls Al Azhar University. | ||
| Abstract | ||
| The current study was planned to follow up the effect of famous mixture used as a hypoglycemic traditional medicine in Saudi Arabia on diabetic albino rats and their effects on some biochemical parameter as DHEA .This study also aimed to study the effect of each plants alone to illustrate the most powerful one of them. The present study was carried out on eighty adult male albino rats (120+20gm b.wt). They were randomly divided into eight groups. First group conserved as control group.The others groups received alloxan to become diabetic .The second group conserved as diabetic, the third group treated with a mixture of plants (0.5gm/120gm b.wt).From he fourth to eight group,the rats treated with Nigella sativa (0.25gm/120gm b.wt),Aloe vera,Ferulaassa-foetid,Boswellia Carterii Birdw and Commiphora myrrha respectively (0.5gm/120gm b.wt.).Our result showed that the body weight was reduced significantly in diabetic group and Nigella sativa treated group. On the other hand, treatment with commiphora myrrha revealed significant increase in body weight gain, while mixture and Aloe vera treated rats recorded insignificant change. Diabetic rats revealed a significant decrease in serum glucose and DHEA-S levels and liver glycogen content, while insignificant difference was recoded in all treated groups. A significant decrease in serum insulin level was observed in diabetic group, Nigella sativa and Ferula assa- foetida treated groups, but insignificant different was recorded in the rest treated groups throughout the experiment. A significant increase in LDH activities in diabetic and Ferula assa- foetida treated groups was recorded while During experimental period. | ||
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