Determination of Liver Enzymes, Lipid Profile, Tumor Necrosis Factor-α and C-Reactive Protein Concentrations in Women in Toxemia of Pregnancy in Tikrit City | ||
| Egyptian Journal of Chemistry | ||
| Article 14, Volume 64, Issue 12, December 2021, Pages 7011-7015 PDF (302.85 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2021.79284.3894 | ||
| Authors | ||
| Maha A. Hamdi1; Alaa S. Shehab1; Sura M. Mahmod2; Shatha A. Hammadi3 | ||
| 1Dept. of Physiology, College of Medicine, Tikrit University, Tikrit 34001, Iraq | ||
| 2Al-Anbbar health office-General heet hospital, Al-Anbar 31001, Iraq | ||
| 3Dept. of gynecology, Sallah Alddin general hospital, Tikrit 34001, Iraq | ||
| Abstract | ||
| Pre-eclampsia is characterized by an increase in blood pressure and proteinuria. The aim of this study was to determine the concentrations of TNF-α in the maternal blood in patients suffering from pre-eclampsia. Patients and methods a cross sectional study was conducted in Sallah Alddin general hospital/Tikrit city from beginning of March to the end of August 2019. The current research focuses on determining of TNF-α level in pregnancy toxemia in Tikrit city- Iraq. Sixty pregnant women are enrolled in the study thirty of them are suffering from hypertension and albumin urea in the third trimester, age (17-36) years and other thirty are healthy pregnant as control age (17-38) years. All blood samples are tested for Tumor Necrosis Factor-α (TNF-α), C- reactive protein (CRP), albumin, uric acid, liver functions, and lipid profile. The results showed a significant increase, for patient’s women, in the serum TNF-α, CRP, liver enzymes, LDL, triglyceride (TG), cholesterol. While the HDL show significant decrease and non-significant differences regarding serum albumin and uric acid between patients and controls. | ||
| Keywords | ||
| Pregnancy toxemia; liver function; tumor necrosis factor (TNF-α); C- reactive protein; uric acid | ||
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