Post-vaccination studies on mice vaccinated against uropathogenic Escherichia coli | ||
| Catrina: The International Journal of Environmental Sciences | ||
| Article 16, Volume 12, Issue 1, 2015, Pages 73-79 PDF (158.3 K) | ||
| Document Type: Original Article | ||
| Authors | ||
| Samira Mansour* 1; Mohammed Elshahedy2; Tarik Rabie3; Hamdy Fetaih2; Jamil Obaid4 | ||
| 1Faculty of Science, Suez Canal University, Egypt | ||
| 2Faculty of Veterinary Medicine, Suez Canal University, Egypt | ||
| 3Faculty of Agriculture, Suez Canal University, Egypt. | ||
| 4Faculty of Science, Suez Canal University, Egypt Faculty of Science, Ibb university, Yemen | ||
| Abstract | ||
| Vaccination is one of the most important strategies for fighting infection. The efficiency of vaccination is determined by many tests that evaluate the immune response vaccine elicit. Here Uropathogenic E. coli vaccines were evaluated by challenge test, indirect haemagglutination test, histopathology, haematology and biochemistry measurements. The results indicate to the benefit of inactivated polyvalent whole cell vaccine and adjuvant-use in immunopotentiation of vaccine. Many measures were used as a good indication and correlated to effectiveness of vaccine as post–vaccination antibody titer, total leukocytic count, neutrophil percent and total protein. Also the histopathology results for dead mice give clear clue to the interpretation of challenge test results. | ||
| Keywords | ||
| albumin; antibodies; Leukocytes; monovalent; polyvalent; protein; vaccine | ||
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