MOLLUSCICIDAL STEROIDAL SAPONINS FROM AGAVE FEROX | ||
| Zagazig Journal of Pharmaceutical Sciences | ||
| Article 9, Volume 7, Issue 1, June 1998, Pages 73-79 PDF (4.18 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zjps.1998.184814 | ||
| Author | ||
| Mortada El-Sayed* | ||
| Laboratory of Medicinal Chemistry, Theodor Bilharz Research Institute, Imbaba, Giza, Egypt. | ||
| Abstract | ||
| Four steroidal saponins were isolated from the methanol extract of the leaves of Agave ferox. On the basis of chemical and spectroscopic evidence, the structures of these saponins were established as yamogenin 3-O-α-L-rhamnopyranosyl- (1→ 2) –[α-L- arabinopyranosyl-(1→3)-β-D-glucopyranoside; yamogenin 3-O-α-L-rhamopyranosyl –(1→ 2 ) [-B-D-glucopyranosyl-(1→4)-6-D- glucopyranoside; gentrogenin 3-O-α-L-rhamnopyranosyl- (1→2)-α-L-arabinopyranosyl- (1→3) - β-D-glucopyranosyl-(1→ 4)-β-D- galactopyranoside and gentrogenin 3-0-a-L- rhamnopyranosyl-(1→2)-B-D-glucopyranosyl(1-→3)-B-D glucopyranosyl- (1→4) -B-D- galactopyranoside. The four saponins were found to possess various molluscicidal activities against Biomphalaria alexandrina snails; the intermediate host of Schistosoma mansoni in Egypt. | ||
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