ONE POT SYNTHESIS, OF 2(1H)-QUINAZOLINONE DERIVATIVES | ||
| Zagazig Journal of Pharmaceutical Sciences | ||
| Article 4, Volume 6, Issue 1, June 1997, Pages 21-25 PDF (3.74 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zjps.1997.184950 | ||
| Author | ||
| Zakaria Abd El-Samii* | ||
| Department of Organic Pharmaceutical Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt | ||
| Abstract | ||
| Condensation of (3-methoxyphenyl)urea or guanidine derivatives (la-e) with a variety of acyl chlorides in polyphosphoric acid leads to intramolecular cyclization with formation of the title compounds (2a-j). Attempted one pot preparation of new tricyclic pyrrolo [3,2,1-ij]-2(2H)-quinazolinone derivatives (3) using (1f) carboxamidoindoline (1f) and acyl chlorides were carried out. | ||
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