Metwally, M., El-Shanawany, A., Bayomi, A., El-Zareh, M. (1995). PMR DETERMINATION OF PRAZIQUANTEL. test, 4(2), 135-142. doi: 10.21608/zjps.1995.186264
Mamdouh Metwally; Abdallah El-Shanawany; Abd El-Aziz Bayomi; Mohsin El-Zareh. "PMR DETERMINATION OF PRAZIQUANTEL". test, 4, 2, 1995, 135-142. doi: 10.21608/zjps.1995.186264
Metwally, M., El-Shanawany, A., Bayomi, A., El-Zareh, M. (1995). 'PMR DETERMINATION OF PRAZIQUANTEL', test, 4(2), pp. 135-142. doi: 10.21608/zjps.1995.186264
Metwally, M., El-Shanawany, A., Bayomi, A., El-Zareh, M. PMR DETERMINATION OF PRAZIQUANTEL. test, 1995; 4(2): 135-142. doi: 10.21608/zjps.1995.186264

PMR DETERMINATION OF PRAZIQUANTEL

Zagazig Journal of Pharmaceutical Sciences
Article 21, Volume 4, Issue 2, December 1995, Pages 135-142    PDF (3.18 M)
Document Type: Original Article
DOI: 10.21608/zjps.1995.186264
Authors
Mamdouh Metwally* 1; Abdallah El-Shanawany2; Abd El-Aziz Bayomi3; Mohsin El-Zareh4
1Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University, Egypt.
2Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazige University, Zagazig, Egypt
3Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Egypt.
4Department of Chemistry, Faculty of Science, Zagazig University, Egypt.
Abstract
Pmr techniques have been used for the determination of praziquantel as sum integeral of the cyclohexane protons as multiplet that appear at 1.1-2 ppm and as compared to the sum integeral of the 1,4-disubstituted aromatic protons system as doublet of doublet that appear at 7.5-8.5 ppm using N,N-dimethylaminobenzaldehyde as internal standard. The obtained results shows % recovery of mean average 100.39. The method is valid for the determination of praziquantel in tablet and in presence of its induced degradation products.
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