Salem, H., Aboul Kheir, A. (1995). DETERMINATION OF PHENOBARBITONE IN TWO AND THREE COMPONENTS FORMULATIONS BY FIRST AND SECOND DERIVATIVE ULTRAVIOLET SPECTROPHOTOMETRY. test, 4(1), 117-125. doi: 10.21608/zjps.1995.186368
Hesham Salem; Afaf Aboul Kheir. "DETERMINATION OF PHENOBARBITONE IN TWO AND THREE COMPONENTS FORMULATIONS BY FIRST AND SECOND DERIVATIVE ULTRAVIOLET SPECTROPHOTOMETRY". test, 4, 1, 1995, 117-125. doi: 10.21608/zjps.1995.186368
Salem, H., Aboul Kheir, A. (1995). 'DETERMINATION OF PHENOBARBITONE IN TWO AND THREE COMPONENTS FORMULATIONS BY FIRST AND SECOND DERIVATIVE ULTRAVIOLET SPECTROPHOTOMETRY', test, 4(1), pp. 117-125. doi: 10.21608/zjps.1995.186368
Salem, H., Aboul Kheir, A. DETERMINATION OF PHENOBARBITONE IN TWO AND THREE COMPONENTS FORMULATIONS BY FIRST AND SECOND DERIVATIVE ULTRAVIOLET SPECTROPHOTOMETRY. test, 1995; 4(1): 117-125. doi: 10.21608/zjps.1995.186368

DETERMINATION OF PHENOBARBITONE IN TWO AND THREE COMPONENTS FORMULATIONS BY FIRST AND SECOND DERIVATIVE ULTRAVIOLET SPECTROPHOTOMETRY

Zagazig Journal of Pharmaceutical Sciences
Article 16, Volume 4, Issue 1, June 1995, Pages 117-125    PDF (4.15 M)
Document Type: Original Article
DOI: 10.21608/zjps.1995.186368
Authors
Hesham Salem* 1; Afaf Aboul Kheir2
1MiST Pharmacy. Menia El-Kamh, Sharkia, Eqypt.
2Chemistry Department, Girls College (Scientific Departments) Riyadh, Saudi Arabia
Abstract
Phenobarbitone has been determined in a ternary mixture with oxyphenonium bromide and meprobamate (mixture A) and in binary mixtures with paracetamol (mixture B) or acetylsalicylic acid (mixture C) using derivative spectrophotometry applying zero-crossing technique of measurement. The combining active ingredients have also been determined. The procedures were proved using laboratory prepared mixtures and their utility in assay of pharmaceutical dosage forms were also presented.
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