El Balkiny, M., Ragab, G., Ayad, M. (1994). DETERMINATION OF TRIMETHOPRIM BY CHARGE-TRANSFER COMPLEX FORMATION. test, 3(2), 132-141. doi: 10.21608/zjps.1994.186488
Mohamed El Balkiny; Gamal Ragab; Magda Ayad. "DETERMINATION OF TRIMETHOPRIM BY CHARGE-TRANSFER COMPLEX FORMATION". test, 3, 2, 1994, 132-141. doi: 10.21608/zjps.1994.186488
El Balkiny, M., Ragab, G., Ayad, M. (1994). 'DETERMINATION OF TRIMETHOPRIM BY CHARGE-TRANSFER COMPLEX FORMATION', test, 3(2), pp. 132-141. doi: 10.21608/zjps.1994.186488
El Balkiny, M., Ragab, G., Ayad, M. DETERMINATION OF TRIMETHOPRIM BY CHARGE-TRANSFER COMPLEX FORMATION. test, 1994; 3(2): 132-141. doi: 10.21608/zjps.1994.186488

DETERMINATION OF TRIMETHOPRIM BY CHARGE-TRANSFER COMPLEX FORMATION

Zagazig Journal of Pharmaceutical Sciences
Article 15, Volume 3, Issue 2, December 1994, Pages 132-141    PDF (4.29 M)
Document Type: Original Article
DOI: 10.21608/zjps.1994.186488
Authors
Mohamed El Balkiny* 1; Gamal Ragab2; Magda Ayad3
1Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt
2Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
3Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University. Zagazig. Egypt.
Abstract
A simple and accurate charge-transfer complex (CT) method for the determination of trimethoprim is presented. The method involved the use of p-chloranil in dioxane: methanol (1:2) medium. The absorbance of the violet colour of the charge-transfer complex was measured at 535 nm against reagent blank. The method permits determination of about 60-480µg ml-1 of trimethoprim in the final solution mixture with mean percentage recovery 98.84± 1.23%
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