Ghallab, A., Allam, A., Abdelhay, S., Abdelwahab, M., Elsayed, R., Abdelalim, A. (2020). Study the Role of Human Papilloma Virus and Laryngopharyngeal Reflux in Adult Vocal Fold Polyps. test, 5(Issue 8 part (1) - (2)), 255-260. doi: 10.21608/bjas.2020.187221
A.F. Ghallab; A.F. Allam; S.A. Abdelhay; M.G. Abdelwahab; R.A. Elsayed; A.A. Abdelalim. "Study the Role of Human Papilloma Virus and Laryngopharyngeal Reflux in Adult Vocal Fold Polyps". test, 5, Issue 8 part (1) - (2), 2020, 255-260. doi: 10.21608/bjas.2020.187221
Ghallab, A., Allam, A., Abdelhay, S., Abdelwahab, M., Elsayed, R., Abdelalim, A. (2020). 'Study the Role of Human Papilloma Virus and Laryngopharyngeal Reflux in Adult Vocal Fold Polyps', test, 5(Issue 8 part (1) - (2)), pp. 255-260. doi: 10.21608/bjas.2020.187221
Ghallab, A., Allam, A., Abdelhay, S., Abdelwahab, M., Elsayed, R., Abdelalim, A. Study the Role of Human Papilloma Virus and Laryngopharyngeal Reflux in Adult Vocal Fold Polyps. test, 2020; 5(Issue 8 part (1) - (2)): 255-260. doi: 10.21608/bjas.2020.187221

Study the Role of Human Papilloma Virus and Laryngopharyngeal Reflux in Adult Vocal Fold Polyps

Benha Journal of Applied Sciences
Article 41, Volume 5, Issue 8 part (1) - (2), December 2020, Pages 255-260    PDF (417.27 K)
Document Type: Original Research Papers
DOI: 10.21608/bjas.2020.187221
Authors
A.F. Ghallab1; A.F. Allam1; S.A. Abdelhay1; M.G. Abdelwahab1; R.A. Elsayed2; A.A. Abdelalim1
1Otorhinolaryngology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt
2Medical Microbiology and Immunology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt
Abstract
There are a few potential reasons for vocal overlap polyps in grown-ups. The mechanical harm is the fundamental driver for polyp arrangement. Laryngopharyngeal reflux and human papilloma infection are conceivable co-factors. The point of this examination was to discover the related parts of laryngopharyngeal reflux and human papilloma infection in the advancement of grown-up vocal crease polyps. This cross-sectional observational investigation included 50 grown-up patients gave vocal crease polyps. Patients were preoperatively evaluated for the presence of laryngopharyngeal reflux utilizing the approved nine-thing reflux indication file and eight-thing reflux discovering score. All patients were exposed to extraction of the laryngeal polyp by microlaryngoscopic medical procedure. The extracted tests were sent for human papilloma infection (HPV) identification by PCR. Laryngopharyngeal reflux (LPR) was introduced in 34 patients (68%). Reflux side effect list went from 6 to 25 (mean 13.06 ± 4.95). Reflux discovering score went from 3 to 18 (mean 10.08 ± 4.32). Seventeen patients (34%) had positive HPV-6. Fifteen patients had positive HPV-6 out of 34 patients determined to have LPR (44.11%), contrasted with just two patients had positive HPV-6 among 16 patients without LPR (12.5%) (P = 0.027). There were critical relations between presence of HPV-6 and both reflux side effect record and reflux discovering score; both were essentially higher among patients with positive HPV-6 (P = 0.028) and (P < 0.001) individually. Both laryngopharyngeal reflux and human papilloma infection assume significant related functions in the improvement of vocal
Keywords
Vocal fold polyp; Human papilloma virus; Laryngopharyngeal reflux
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