Salem, A., El-Saiedi, S., Soliman, N., Badr, A., Hassan, A., El-Sisi, A. (2021). Outcome of Patients having Congenital Anomalies of the Kidney and Urinary Tract Associated with Congenital Heart Diseases in Pediatric Cardiac ICU.. test, 16(1), 34-48. doi: 10.21608/geget.2021.187833
Amr Salem; Sonia El-Saiedi; Nevine Soliman; Ahmed Badr; Ahmed Hassan; Amal El-Sisi. "Outcome of Patients having Congenital Anomalies of the Kidney and Urinary Tract Associated with Congenital Heart Diseases in Pediatric Cardiac ICU.". test, 16, 1, 2021, 34-48. doi: 10.21608/geget.2021.187833
Salem, A., El-Saiedi, S., Soliman, N., Badr, A., Hassan, A., El-Sisi, A. (2021). 'Outcome of Patients having Congenital Anomalies of the Kidney and Urinary Tract Associated with Congenital Heart Diseases in Pediatric Cardiac ICU.', test, 16(1), pp. 34-48. doi: 10.21608/geget.2021.187833
Salem, A., El-Saiedi, S., Soliman, N., Badr, A., Hassan, A., El-Sisi, A. Outcome of Patients having Congenital Anomalies of the Kidney and Urinary Tract Associated with Congenital Heart Diseases in Pediatric Cardiac ICU.. test, 2021; 16(1): 34-48. doi: 10.21608/geget.2021.187833

Outcome of Patients having Congenital Anomalies of the Kidney and Urinary Tract Associated with Congenital Heart Diseases in Pediatric Cardiac ICU.

GEGET
Article 2, Volume 16, Issue 1, June 2021, Pages 34-48    PDF (567.93 K)
Document Type: Original Article
DOI: 10.21608/geget.2021.187833
Authors
Amr Salem* 1; Sonia El-Saiedi2; Nevine Soliman1; Ahmed Badr1; Ahmed Hassan3; Amal El-Sisi2
1Department of Pediatrics, Pediatric Nephrology Unit, Faculty of Medicine, Cairo University.
2Department of Pediatrics, Pediatric Cardiology Unit, Faculty of Medicine, Cairo University.
3Department of Pediatrics, Military Hospital Ghamra.
Abstract
Introduction: Congenital heart defects are the most common of all congenital malformations and there is a higher incidence of urinary tract anomalies in these cases 
Aim of the study: Our study aims to identify the prevalence and phenotypes of congenital anomalies of the kidney and urinary tract (CAKUT) among cases with congenital heart diseases admitted to cardiac ICU.
Methods: Eighty seven neonates and infants with congenital heart diseases were admitted to the cardiac ICU. Patients were assessed for CAKUT mainly via pelvi-abdominal US screening to exclude gross anomalies, along with clinical, laboratory and other imaging findings during the PICU admission. 
Results: Patients diagnosed with CAKUT formed 9.2%. Although there was no statistical correlation between certain types of congenital heart diseases (CHD) and certain types of CAKUT, there was a higher incidence among patients with cyanotic CHD (11.3%) rather than in patients with acyanotic heart CHD (6.9%). There was a strong correlation between the presence of CAKUT and the length of PICU stay, the need for higher doses of inotropes and the need for renal dialysis. There was a higher incidence with positive history of maternal chronic illness and maternal drug intake during pregnancy.
Conclusion: CAKUT is common among patients admitted into the PICU with CHD. CAKUT is associated with increased morbidity, length of PICU stay and poor outcome. Pelvi-abdominal US is one of the gold standard tools for screening.
 
Keywords
Congenital Anomalies of Kidney and Urinary Tract; Congenital Heart Disease; Pelvi-Abdominal Ultrasonography; PICU
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