Study of the Value of Urinary Vitamin D-Binding Protein as a Prognostic Biomarker in Cases of Childhood Idiopathic Nephrotic Syndrome and its Relation to Calcium /Phosphorus Metabolism. | ||
| GEGET | ||
| Article 5, Volume 16, Issue 1, June 2021, Pages 71-82 PDF (270.02 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/geget.2021.80499.1026 | ||
| Authors | ||
| Mohammad Sharaf1; Khaled Awwad2; Asmaa Ahmed Awad Gad El Rab* 3; Dina Aly Ragab4 | ||
| 1Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt. | ||
| 2Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt | ||
| 3Department of Pediatrics, Ministry of Health, Egypt. | ||
| 4Department of Clinical Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt. | ||
| Abstract | ||
| Introduction: Nephrotic syndrome (NS) is a common chronic kidney disease in childhood and it is mostly idiopathic. Aim of the Study: To determine if uVDBP measurements can be used as a non-invasive prognostic biomarker in cases of childhood idiopathic NS and its relation to Ca/P metabolism. Methods: This prospective study was carried out on children who were newly diagnosed with idiopathic nephrotic syndrome presented to the pediatric nephrology unit, Ain Shams University hospitals during the period from November 2019 till May 2020. Results: The present study showed that levels of uVDBP were significantly higher in cases than in healthy control children. Conclusion: We can conclude that uVDBP measurements represent a non-invasive prognostic biomarker in cases of childhood idiopathic NS. | ||
| Keywords | ||
| Childhood idiopathic nephrotic syndrome; Ca /P metabolism; urinary vitamin D-binding protein | ||
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