Protective effect of ginseng against toxic effect of ochratoxin (OA) in kidney of male rats | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 13, Volume 7, Issue 1, April 2002, Pages 151-167 PDF (835.07 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2002.18848 | ||
| Author | ||
| Fatma A. Morsy | ||
| Basic Meidcal Sciences Department, Pathology Researches, National Research Center | ||
| Abstract | ||
| ' ( ) * % * ( * + , * - * . /0'1 + !% (23 / / !45 !1 & % *3 + * * / ! (231 ! (in before OA injection following the same previous schedule of injections. The remaining groups were injected with ginseng only. Paraffin sections were used for histopathological study. For histochemical investigations, sections were stained to demonstrate the glycogen, DNA, protein and alkaline phosphatase activity. OA showed sever histopathological effects on kidney demonstrated as pyknosis in some tubules and vacuolar degeneration in tubular epithelial cells. Also cell debris and hyalin casts were present in lumen of tubules. The histochemical results showed a decrease in DNA, protein content and negative reaction for glycogen and alkaline phsophatase activity. The ginseng was found to reduce the deleterious effect of OA. | ||
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