Comparison Between Gadolinium Enhanced Susceptibility Weighted Imaging And Conventional T1-Weighted Imaging In Optimizing The Recognition Of Active Plaques Of Multiple Sclerosis | ||
| Zagazig University Medical Journal | ||
| Article 23, Volume 28, Issue 6, November 2022, Pages 1368-1376 PDF (401.37 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zumj.2021.95908.2347 | ||
| Authors | ||
| Ahmed Mohamed Alsowey* 1; Sara Mohamed Rady2; HossamEldin Mansour Abdelrahman3; Heba Abdelmonem Elsayed4 | ||
| 1Radiodiagnosis Department; Faculty of medicine, Zagazig University, Egypt. | ||
| 2Radiodiagnosis department, Faculty of medicine, Zagazig university, Zagazig, Egypt. | ||
| 3Radiodiagnosis Department , Faculty of medicine, Zagazig University, Zagazig, Egypt. | ||
| 4Radiodiagnosis Department, Faculty of medicine, Zagazig university, Zagazig Egypt. | ||
| Abstract | ||
| Background: The Gd-SWI sequence is a new important magnetic resonance imaging sequence that has been applied currently due to its ability to optimize the recognition of active plaques of MS and has a higher accurate performance than gadolinium T1WI that is currently used in clinical practice. Aim: comparing the performance of the Gd-SWI sequence with the performance of other used sequences in clinical practice in detection of blood brain barrier (BBB) dysfunctions in MS plaques. Methods: in this retrospective study, Twenty four patients were involved (16 females and 8males, their age ranging from 20- 42 years with the mean age 26.33 years), they were divided into two groups: 8 active cases and 22 inactive cases clinically and radiologically proven MS cases for MRI diagnosis and follow up. Results: Two thirds of the studied group (66.7 %) had inactive lesions and one third (33.3 %) had active ones with (12.5 %) of both active and inactive lesions were progressive. There was higher ability of post-contrast SWI to demonstrate active plaques than post-contrast TIWI and there was highly statistically significance and good agreement (kappa=0.71) with 89.5% percent of agreement between post contrast enhanced lesions by SWI and T1 and statistically highly significant difference (p < 0.001). Conclusions: Gadolinium –SWI technique improved detection accuracy of MS- contrast-enhanced plaques better than Gd-T1 SE, including their locations and morphologies. | ||
| Keywords | ||
| Keywords: Susceptibility Weighted Imaging; Multiple sclerosis; Magnetic Resonance Imaging; T1WI | ||
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