" The Anti-Inflammatory Effect of Garcinia Mongostana Extract in Treatment of Chronic Periodontitis clinical and laboratory study" | ||
| Mansoura Journal of Dentistry | ||
| Article 10, Volume 7, Issue 2, April 2020, Pages 46-51 PDF (324.06 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjd.2020.199110 | ||
| Abstract | ||
| Background:Patients with choric periodontal diseases have high levels of lactate dehaydrogenase(LDH) in gingival cervical fluid (GCF) . Garcinia mangostana (MGA), more popularly known as mangosteen can be used as an adjunct to SRP to provide a new dimension to periodontal therapy . Aim: To evaluate the effect of garcinia mangostana extract gel as a local drug delivery in treatment of chronic periodontitis patients. Assessment of Lactate dehydrogenase enzyme levels in GCF of such patients. Subjects and methods: Ten patients (MGA group) were treated with SRP, and the subgingival application of mangostana gel was used as local drug delivery. Ten patients (chlorhexidine gel) were treated with SRP and chlorhexidine gel. Ten patient treated with SRP only . Five group (control group).Clinical parameters were recorded and at the one month and samples of GCF were analyzed using ldh ELISA kit for all group. Results:All periodontal parameters(PI,BOP,PPD,CAL) and Laboratory analysis results LDH were reduced significantly by local drug delivery treatment. Conclusion:Scaling and root planning (SRP) is an effective treatment in chronic periodontitis patients associated with local drug deliveryرررررر therapy (mangostana gel) can improve the GCF level of one of the inflammatory biomarkers (LDH) .ر | ||
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