The effect of Erbium:YAG Laser for the Fibronectin Expression in Gingival Epithelium with Nifedipine induced Gingival Overgrowth | ||
| Egyptian Dental Journal | ||
| Article 16, Volume 67, Issue 4 - Serial Number 3, October 2021, Pages 3259-3269 PDF (2.6 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/edj.2021.88267.1754 | ||
| Authors | ||
| rasha mostafa* 1; Marwa Tawfiq2 | ||
| 1Lecturer, Oral Medicine and Periodontology Department , Faculty of Dentistry Cairo University, Cairo, Egypt. Oral Medicine and Periodontology Department, Faculty of Dentistry Badr University in Cairo, (BUC), Cairo, Egypt. | ||
| 2Lecturer, Oral medicine, Periodontology, and Diagnosis, Faculty of Oral and Dental Medicine Beni-Suef University. | ||
| Abstract | ||
| Gingival overgrowth is one of the side- effects seen as a result of the regular administration of the calcium channel blocker anti-hypertensive drug Nifedipine. Fibronectin (FN), is an adhesive high molecular weight extra cellular matrix glycoprotein which plays an important role in influencing cell growth, adhesion, migration as well as extracellular matrix organization. It also contributes to fibroblast attachment and proliferation, and participates in the regulation of tissue fibrosis. Erbium: YAG laser was approved in 1997 by the U.S. Food and Drug Administration for hard and soft tissue treatment in dentistry. Several studies have been published to demonstrate its efficacy for bone cutting, plaque and subgingival calculus removal, as well as having an antiseptic effect on both soft and hard periodontal tissues. Conventional scaling in combination with Erbium: YAG laser has unexpectedly showed complete healing with (2 normalization of the gingiva, making further surgical treatment for gingival volume reduction unecessary. | ||
| Keywords | ||
| gingival enlargement; fibronectin; immunohistochemical; nefidipine; eberium YAG laser | ||
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